Table 2

Baseline characteristics of participants in the included studies

Study IDWatanabe et al16Mangner et al17Landes et al18
Demographics
Age (years)
Mean (SD) or median (range)
With cancer83 (80–87)*81 (77–84)78.8±7.5*
Without cancer85 (82–88)81 (77–84)81.3±7.1
Male sex
n (%)
With cancer21 (45)59 (59.6)*138 (62)*
Without cancer232 (33)628 (42.7)1135 (45)
BMI (kg/m2)
Mean (SD) or median (range)
With cancer23.6 (21.0–26.2)*26.6 (23.9–29.5)26.6±4.8*
Without cancer21.7 (19.2–24.1)27.4 (24.4–31.2)28±5.0
Diabetes mellitus
n (%)
With cancer14 (30)38 (38.4)62 (28)
Without cancer175 (25)640 (43.6)908 (36)
Hypertension
n (%)
With cancer35 (75)92 (93.9)169 (76)*
Without cancer531 (75.6)1365 (93.6)2320 (92)
Comorbidities
Previous MI
n (%)
With cancer5 (11)17 (17.3)29 (13)
Without cancer59 (8)175 (12.0)226 (9)
PAD
n (%)
With cancer11 (23)8 (8.2)35 (16)
Without cancer108 (15)171 (11.7)252 (14)
Cerebrovascular disease
n (%)
With cancer5 (11)11 (11.2)24 (11)
Without cancer101 (14)143 (9.8)452 (18)
COPD
n (%)
With cancer15 (32)*13 (13.1)37 (17)
Without cancer138 (20)248 (16.9)428 (17)
Preprocedural parameters
STS score (%)
Mean (SD) or median (range)
With cancer5.4 (3.4–7.5)*6.0 (3.8–10.9)4.9±3.4*
Without cancer7.0 (4.6–9.4)6.7 (4.1–10.6)6.2±4.4
Aortic valve area (cm2)
Mean (SD) or median (range)
With cancer0.65 (0.56–0.74)0.7 (0.5–0.8)0.72±0.22*
Without cancer0.62 (0.50–0.74)0.7 (0.5–0.8)0.65±0.20
Mean pressure gradient (mm Hg)
Mean (SD) or median (range)
With cancer50.4 (38.8–62.1)44 (35–58)49±20
Without cancer48.0 (36.2–59.9)42 (33–52)48±16
LVEF (%)
Mean (SD) or median (range)
With cancer65.9 (54.0–66.4)57 (45–64)56±14
Without cancer65.0 (59.9–70.5)58 (45–65)56±8
  • *P<0.05 for patients with cancer compared with patients without cancer in each study.

  • BMI, body mass index; COPD, chronic obstructive pulmonary disease; LVEF, left ventricular ejection fraction; MI, myocardial infarction; PAD, peripheral arterial disease; STS, Society of Thoracic Surgeons.