Variables | Univariate | *Bivariate models with adjusted postprocedural MD | †Bivariate models with adjusted ∆MD | |||
HR (95% CI) | P value | HR (95% CI) | P value | HR (95% CI) | P value | |
CAD history | 1.51 (0.63 to 3.62) | 0.35 | 1.47 (0.61 to 3.52) | 0.38 | 1.55 (0.65 to 3.71) | 0.32 |
1.23 (1.01 to 1.50) * | 0.05 | 1.49 (1.19 to 1.88) † | 0.001 | |||
Gender | 1.80 (0.75 to 4.31) | 0.19 | 1.84 (0.77 to 4.42) | 0.17 | 1.65 (0.69 to 3.98) | 0.27 |
1.23 (1.01 to 1.49) * | 0.04 | 1.47 (1.17 to 1.84) † | 0.001 | |||
GLS per % increase | 1.03 (0.92 to 1.15) | 0.67 | 0.99 (0.88 to 1.11) | 0.88 | 0.99 (0.89 to 1.12) | 0.97 |
1.24 (1.00 to 1.55) * | 0.05 | 1.50 (1.18 to 1.91) † | 0.001 | |||
Logistic EuroSCORE | 1.01 (0.97 to 1.05) | 0.58 | 1.01 (0.97 to 1.05) | 0.69 | 1.01 (0.97 to 1.05) | 0.69 |
1.23 (0.99 to 1.53) * | 0.06 | 1.50 (1.19 to 1.89) † | 0.001 | |||
LVEF per % increase | 0.98 (0.94 to 1.03) | 0.41 | 0.99 (0.95 to 1.03) | 0.57 | 0.99 (0.95 to 1.03) | 0.53 |
1.23 (1.00 to 1.51) * | 0.05 | 1.49 (1.18 to 1.88) † | 0.001 | |||
MD per 10 ms increase | 1.23 (1.01 to 1.51) | 0.04 | ||||
∆MD per 10 ms increase | 1.50 (1.18 to 1.89) | 0.001 | ||||
New LBBB (yes/no) | 1.11 (0.41 to 3.01) | 0.84 | 0.94 (0.34 to 2.57) | 0.90 | 0.61 (0.21 to 1.73) | 0.35 |
1.24 (1.01 to 1.52) * | 0.04 | 1.56 (1.22 to 1.99) † | <0.001 | |||
∆QRS duration, per 10 ms increase | 1.01 (0.99 to 1.03) | 0.20 | 1.10 (0.94 to 1.29) | 0.24 | 1.02 (0.86 to 1.22) | 0.80 |
1.28 (1.03 to 1.59) * | 0.03 | 1.58 (1.23 to 2.03) † | <0.001 | |||
∆ZVA, per mm Hg m2/mL decrease | 1.04 (0.72 to 1.51) | 0.83 | 1.12 (0.76 to 1.64) | 0.58 | 1.24 (0.85 to 1.82) | 0.26 |
1.20 (0.94 to 1.53) * | 0.14 | 1.55 (1.17 to 2.05) † | 0.002 |
Rows marked with footnote symbols (*, †) contain bivariate HR values for postprocedural MD and ∆MD, respectively.
AS, aortic stenosis; CAD, coronary artery disease; GLS, global longitudinal strain; LBBB, left bundle branch block; LVEF, left ventricular ejection fraction; MD, mechanical dispersion; TAVI, transcatheter aortic valve implantation; ZVA, valvulo-arterial impedance.