Baseline characteristics of study participants by incident venous thromboembolism (VTE): the Multi-Ethnic Study of Atherosclerosis, 2000–2002*
| Baseline characteristics | Total | No VTE | VTE | P value |
| N | 6479 | 6243 | 236 | – |
| Heart rate, bpm | 63.1±9.6 | 63±9.6 | 64.6±11.1 | 0.01 |
| Heart rate, bpm* | 62 (56–69) | 62 (56–69) | 63 (56–73) | 0.04 |
| Age, years | 62.1±10.2 | 62±10.2 | 66.6±9.4 | <0.001 |
| Women | 3423 (52.8%) | 3296 (52.8%) | 127 (53.8%) | 0.76 |
| Race/ethnicity | <0.001 | |||
| White | 2504 (38.7%) | 2403 (38.5%) | 101 (42.8%) | – |
| Black | 1757 (27.1%) | 1668 (26.7%) | 89 (37.7%) | – |
| Hispanic | 1431 (22.1%) | 1394 (22.3%) | 37 (15.7%) | – |
| Chinese | 787 (12.2%) | 778 (12.5%) | 9 (3.8%) | – |
| Education | 0.69 | |||
| Less than high school | 1176 (18.2%) | 1134 (18.2%) | 42 (17.8%) | – |
| High school or vocational school | 2683 (41.4%) | 2579 (41.3%) | 104 (44.1%) | – |
| College, graduate or professional school | 2620 (40.4%) | 2530 (40.5%) | 90 (38.1%) | – |
| Smoking status | 0.33 | |||
| Never | 3268 (50.4%) | 3160 (50.6%) | 108 (45.8%) | – |
| Former | 2381 (36.8%) | 2285 (36.6%) | 96 (40.7%) | – |
| Current | 830 (12.8%) | 798 (12.8%) | 32 (13.6%) | – |
| BMI, kg/m2 | 28.3±5.4 | 28.2±5.4 | 30.5±6.2 | <0.001 |
| Physical activity, MET-minutes/week† | 4020 (1980–7515) | 4035 (1980–7545) | 3554 (1864–6544) | 0.13 |
| Diabetes | 814 (12.6%) | 777 (12.5%) | 37 (15.7%) | 0.14 |
| eGFR, ml/min per 1.73 m2 | 77.7±16.2 | 77.9±16.1 | 73.5±18.4 | <0.001 |
| AV nodal blocker medication | 829 (12.8%) | 792 (12.7%) | 37 (15.7%) | 0.18 |
| Anticoagulant use | 24 (0.4%) | 20 (0.3%) | 4 (1.7%) | 0.001 |
| Aspirin use | 1631 (25.2%) | 1556 (24.9%) | 75 (31.8%) | 0.02 |
| hsCRP, mg/L† | 1.9 (0.8–4.2) | 1.9 (0.8–4.2) | 2.5 (1.2–4.5) | 0.002 |
| Interleukin-6, pg/mL† | 1.2 (0.8–1.9) | 1.2 (0.8–1.9) | 1.4 (0.9–2.6) | <0.001 |
| Fibrinogen, mg/dL† | 337 (295–388) | 337 (294–387) | 346 (309–407) | 0.01 |
| D-dimer, μg/mL† | 0.2 (0.1–0.4) | 0.2 (0.1–0.4) | 0.4 (0.2–0.6) | <0.001 |
*Data are presented as mean±SD for continuous variables and as frequency (percentage) for categorical variables, unless otherwise specified. P values derived from two samples t-test or Mann-Whitney test for continuous variables and X2 test for categorical variables.
†Data presented as median (25–75th percentile).
AV, atrioventricular; BMI, body mass index; bpm, beats per minute; eGFR, estimated glomerular filtration rate; hsCRP, high-sensitivity C reactive protein; MET, metabolic equivalent of task.