Table 4

Partial correlations of resting heart rate with inflammatory/coagulation factors: the Multi-Ethnic Study of Atherosclerosis, 2000–2002*

MarkerWhole cohortMalesFemales
Nr (p value)Nr (p value)Nr (p value)
hs-CRP67140.15 (p<0.001)31730.18 (p<0.001)35410.12 (p<0.001)
Interleukin-665760.15 (p<0.001)31010.17 (p<0.001)34750.13 (p<0.001)
Fibrinogen67210.15 (p<0.001)31810.19 (p<0.001)35400.13 (p<0.001)
D-dimer67210.03 (p=0.005)31820.04 (p=0.02)35390.03 (p=0.12)
VWF9920.10 (p=0.002)4250.07 (p=0.14)5670.12 (p=0.01)
Factor VIII67170.12 (p<0.001)31790.11 (p<0.001)35380.12 (p<0.001)
PAP65840.05 (p<0.001)31190.08 (p<0.001)34650.002 (p=0.91)
PAI-19680.13 (p<0.001)4180.16 (p=0.002)5500.11 (p=0.01)
STM9920.03 (p=0.39)426−0.01 (p=0.77)5660.08 (p=0.07)
E-selectin9940.16 (p<0.001)4260.21 (p<0.001)5680.11 (p=0.01)
ICAM-126100.07 (p<0.001)11460.07 (p=0.03)14640.07 (p=0.01)
  • r, Spearman’s correlation.

  • *Adjusted for age, sex (except in sex stratified analysis), and race/ethnicity.

  • hsCRP, high sensitivity C reactive protein; ICAM-1, Intercellular adhesion molecule 1; PAI-1, plasminogen activator inhibitor-1; PAP, plasmin–antiplasmin; STM, soluble thrombomodulin; VWF, von Willebrand factor.