| B. Interrogated vessel features | Total (n=504) |
| Lesion location | |
| LAD | 348 (69.0%) |
| LCx | 56 (11.1%) |
| RCA | 100 (19.8%) |
| Three-dimensional QCA | |
| RD (mm) | 2.8 (2.5–3.1) |
| MLD (mm) | 1.4 (1.1–1.7) |
| Diameter stenosis (%) | 49.6±12.0 |
| Area stenosis (%) | 66.7 (55.6–75.3) |
| Lesion length (mm) | 18.4 (13.1–24.0) |
| fQFR | 0.78 (0.72–0.87) |
| cQFR | 0.79 (0.74–0.88) |
| Invasive physiological indices | |
| FFR | 0.81 (0.74–0.87) |
| CFR | 2.7 (1.8–3.7) |
| IMR | 20.1 (13.4–30.0) |
| Corrected IMR | 19.0 (12.6–27.5) |
| Baseline, Tmn (s) | 0.84 (0.59–1.18) |
| Hyperaemic, Tmn (s) | 0.30 (0.21–0.46) |
| Duke jeopardy score | 2 (2–6) |
Variables are expressed as n (%), median (IQR) or mean±SD. IMR correction was performed using Yong’s formula.
CFR, coronary flow reserve; cQFR, contrast-flow quantitative flow ratio; FFR, fractional flow reserve; fQFR, fixed-flow quantitative flow ratio; IMR, index of microcirculatory resistance; LAD, left anterior descending artery; LCx, left circumflex artery; MLD, minimal lumen diameter; QCA, quantitative coronary angiography; RCA, right coronary artery; RD, reference diameter; Tmn, mean transit time.