Table 4

Per cent change in the age-adjusted PR for CCS ≥10 in the US-White men with the addition of lipids/lipoproteins

Robust Poisson regression modelsRace/EthnicityPer cent change in PR*Lipids and lipoproteins
PR (95% CI)PR (95% CI)
Age2.14 (1.46 to 3.13)
Age and standard lipids
 Age+LDL-C2.12 (1.45 to 4.00)–0.901.28 (1.08 to 1.51)
 Age+HDL-C1.99 (1.34 to 2.94)–7.000.85 (0.68 to 1.06)
 Age+triglycerides2.17 (1.48 to 3.17)–0.471.41 (1.05 to 1.92)
Age and NMR-measured lipoprotein particles
Age and LDL particles
 Age+total LDL-P2.19 (1.49 to 3.20)+2.341.33 (1.13 to 1.58)
 Age+small LDL-P2.10 (1.44 to 3.08)–1.871.29 (1.08 to 1.49)
 Age+large LDL-P2.13 (1.45 to 3.12)–0.470.91 (0.77 to 1.08)
 Age+IDL-P2.22 (1.51 to 3.25)+3.741.25 (1.08 to 1.45)
 Age+LDL particle size2.17 (1.48 to 3.18)+1.400.84 (0.71 to 1.01)
Age and HDL particles
 Age+total HDL-P2.18 (1.47 to 3.23)+1.871.03 (0.84 to 1.26)
 Age+small HDL-P2.04 (1.34 to 3.10)–4.671.08 (0.89 to 1.32)
Age+medium HDL-P2.35(1.54to3.59)+9.811.12 (0.93 to 1.37)
Age+large HDL-P1.62(1.03to2.54)24.300.72 (0.54 to 0.95)
Age+HDL particle size1.73(1.09to2.74)19.160.80 (0.63 to 1.00)
Age and VLDL particles
 Age+total VLDL-P2.16 (1.48 to 3.16)+0.901.13 (0.97 to 1.31)
 Age+small VLDL-P2.17 (1.47 to 3.16)+1.401.04 (0.87 to 1.25)
 Age+medium VLDL-P2.15 (1.47 to 3.14)+0.471.15 (0.95 to 1.39)
Age+large VLDL-P†2.00(1.32to2.90)6.541.19 (1.01 to 1.42)
Age+VLDL particle size2.00(1.36to2.92)6.541.16 (1.00 to 1.34)
  • Bold font indicates a major change (>5%) in PR for race/ethnicity.

  • Each lipid or lipoprotein was modelled separately in a model adjusted for age.

  • Per cent change in PR for race compared with the age-adjusted model.

  • *Per cent change in PR compared with age-adjusted model was calculated as: ((PR for race/ethnicity in the age-adjusted model)–(PR for race in a given respective model))×100/(PR for race/ethnicity in an age-adjusted model).

  • †Medium VLDL-P and large VLDL-P numbers were log-transformed after the addition of one unit. All other continuous variables were standardised.

  • CCS, Agatston Coronary Calcium Score; HDL-C, high-density lipoprotein cholesterol; HDL-P, high-density lipoprotein particles; IDL-P, intermediate-density lipoprotein particles; LDL-C, low-density lipoprotein cholesterol; LDL-P, low-density lipoprotein particles; PR, prevalence ratio; VLDL-P, very low-density lipoprotein particles.