Age-adjusted association (PR (95% CI)) of lipids and lipoproteins subfractions with the CCS ≥10 in US-White men in Allegheny County, USA, and Japanese men in Kusatsu, Japan
| Lipids and lipoproteins | US-White men (n=270) | Japanese men (n=300) |
| Standard lipids | ||
| LDL-C | 1.23 (0.98 to 1.54) | 1.35 (1.04 to 1.76) |
| HDL-C | 0.79 (0.59 to 1.05) | 0.94 (0.67 to 1.33) |
| Triglycerides | 1.48 (1.03 to 2.12) | 1.28 (0.74 to 2.22) |
| NMR-measured lipoprotein particles | ||
| LDL particles | ||
| Total LDL-P | 1.34 (1.06 to 1.70) | 1.32 (1.04 to 1.69) |
| Small LDL | 1.28 (1.07 to 1.54) | 1.29 (1.00 to 1.67) |
| IDL | 1.2743 (1.07 to 1.51) | 1.23 (0.95 to 1.58) |
| Large LDL | 0.90 (0.74 to 1.07) | 1.01 (0.72 to 1.40) |
| LDL particle size | 0.81 (0.65 to 0.99) | 0.94 (0.67 to 1.34) |
| HDL particles | ||
| Total HDL-P | 0.94 (0.70 to 1.24) | 1.18 (0.88 to 1.56) |
| Small HDL | 0.89 (0.70 to 1.13) | 1.39 (1.01 to 1.92) |
| Medium HDL | 1.21 (0.90 to 1.62) | 1.08 (0.82 to 1.41) |
| Large HDL | 0.76 (0.54 to 1.08) | 0.68 (0.42 to 1.00) |
| HDL particle size | 0.88 (0.68 to 1.12) | 0.67 (0.44 to 1.00) |
| VLDL particles | ||
| Total VLDL-P | 1.13 (0.93 to 1.36) | 1.13 (0.88 to 1.45) |
| Small VLDL | 1.00 (0.77 to 1.29) | 1.11 (0.87 to 1.43) |
| Medium VLDL | 1.12 (0.93 to 1.39) | 1.24 (0.88 to 1.75) |
| Large VLDL | 1.23 (1.00 to 1.53) | 1.15 (0.89 to 1.50) |
| VLDL particle size | 1.26 (1.07 to 1.49) | 0.92 (0.69 to 1.24) |
Each lipid or lipoprotein is modelled separately, adjusted for age.
CCS, Agatston Coronary Calcium Score; HDL-C, high-density lipoprotein cholesterol; HDL-P, high-density lipoprotein particles; IDL, intermediate-density lipoprotein; LDL-C, low-density lipoprotein cholesterol; LDL-P, low-density lipoprotein particles;NMR, nuclear magnetic resonance; PR, prevalence ratio; VLDL-P, very low-density lipoprotein particles.