Variable | Mothers with ASD n=310 | References n=3677 | P value |
Maternal age, years (mean±SD) | 29.9±5.0 | 29.9±4.9 | 0.902 |
Maternal prepregnancy BMI, kg/m2* (mean±SD) | 24.1±4.7 | 24.6±8.2 | 0.242 |
Height, cm* (mean±SD) | 168.9±50.8 | 166.3±24.1 | 0.092 |
Smoker, n (%)† | 60 (21.5) | 661 (19.7) | 0.705 |
Paternal age, years (mean±SD) | 33.0±6.1 | 32.3±5.6 | 0.007 |
Births, n | 559 | 6580 | – |
Singleton birth, n | 519 | 6324 | – |
Multiple birth, n | 40 | 256 | – |
Multiple birth, % | 7.2% | 3.9% | 0.001 |
IVF treatment, n (%) | 33 (10.6) | 119 (3.2) | <0.001 |
Maternal age at IVF treatment, years (mean±SD) (range) | 29.6±0.90 (21.3–40.1) | 30.8±0.36 (20.8–41.4) | – |
Multiple pregnancy following IVF, n (%) | 8 (20.0) | 24 (9.4) | 0.055 |
Previous miscarriage, n (%) | 54 (17.4) | 602 (16.4) | 0.753 |
*Data were missing for BMI and height in 139 mothers with ASD and 1487 references.
†Data were missing for smoking in 32 mothers with ASD and 336 references.
ASD, atrial septal defect ; BMI, body mass index; IVF, in vitro fertilisation.