Table 1

Characteristics and comorbidities for patients with long QT syndrome (LQTS) and their matched controls

DemographicsLQTS (463)Controls (2315)P value
N%N%
Age at diagnosis mean, (SD)35.6(±20.9)35.8(±21.0)0.836
Sex, male17638.088038.01.000
Cardiovascular comorbidities
 Atrial fibrillation306.5532.3<0.001
 Venous thromboembolism102.2411.80.569
 Peripheral vascular disease40.9130.60.446
 Acute myocardial infarction143.0341.50.019
Metabolic comorbidities
 Diabetes mellitus173.7421.80.011
 Hypothyroidism51.1321.60.604
Neurological comorbidities
 Any neurological disease10222.028512.3<0.001
 Episodic and paroxysmal disorders6313.61456.3<0.001
 Nerve and plexus disorders306.5974.20.031
 Polyneuropathies71.5261.10.481
 Myoneural junction30.650.20.113
 Cerebral palsy30.670.30.257
 Hearing loss153.2391.70.027
Psychiatric comorbidities
 Any psychiatric disorder6013.02109.10.010
 Organic mental disorders224.8733.20.084
 Mental disorders due to substance use296.3984.20.056
 Affective disorders91.9401.70.747
 Neurotic and somatoform disorders143.0502.20.258