Table 1

Patient characteristics

Not using snus (n=68 168)Using snus (n=6790)Missing (%)P value
Demographics
 Age67.6 (±11.1)61.0 (±10.2)0.0<0.001
 Age >75 years17 252 (25.3)527 (7.8)0.0<0.001
 Male45 397 (67.4)6476 (95.4)0.0<0.001
 Body mass index27.3 (±6.0)28.3 (±5.8)11.1<0.001
Smoking status0.9<0.001
  Never smoked31 251 (46.2)1674 (24.9)
  Former smoker22 824 (33.8)3353 (49.9)
  Current smoker13 515 (20.0)1693 (25.2)
Comorbidities
 Diabetes13 117 (19.3)1201 (17.7)0.10.002
  Insulin dependent4570 (6.7)412 (6.1)0.704
 Hypertension37 769 (55.6)3356 (49.5)0.4<0.001
 Hyperlipidaemia22 767 (33.6)2117 (31.3)0.6<0.001
 Estimated GFR78.3 (±18.8)85.3 (±17.1)27.0<0.001
CKD stage27.0<0.001
  Chronic kidney disease stage I-II41 571 (83.4)4485 (91.9)
  Chronic kidney disease stage III7558 (15.2)358 (7.3)
  Chronic kidney disease stage IV-V723 (1.5)36 (0.7)
 COPD3167 (4.6)286 (4.2)00.111
 Peripheral artery disease1700 (2.5)151 (2.2)00.185
 Previous stroke3366 (4.9)227 (3.3)0<0.001
 Cancer1357 (2.0)117 (1.7)00.142
 Heart failure1840 (2.7)122 (1.8)0<0.001
In-hospital characteristics
Inclusion time0.0<0.001
  2009–201330 956 (45.4)2918 (43.0)
  2014–201837 212 (54.6)3872 (57.0)
Indication0.00.016
  Stable CAD12 742 (18.7)1178 (17.3)
  UA/NSTEMI34 056 (50.0)3485 (51.3)
  STEMI21 370 (31.3)2128 (31.3)
Medical treatments
 Upstream DAPT54 149 (79.4)5479 (80.7)0.00.014
 Aspirin66 551 (97.6)6651 (98.0)0.00.091
 Clopidogrel29 115 (42.7)2609 (38.4)0.0<0.001
 Prasugrel1452 (2.1)202 (3.0)0.0<0.001
 Ticagrelor36 674 (53.8)3925 (57.8)0.0<0.001
 Heparin60 732 (89.1)6169 (90.9)0.0<0.001
 Bivalirudin17 388 (25.5)1728 (25.4)0.00.916
 LMWH3529 (5.2)268 (3.9)0.0<0.001
 Fondaparinux18 258 (26.8)1941 (28.6)0.00.001
Procedure characteristics
Vascular approach0.0<0.001
  Femoral9200 (13.5)796 (11.7)
  Other58 967 (86.5)5994 (88.3)
Diseased vessels0.40.001
  One37 958 (55.9)3933 (58.2)
  Two19 990 (29.5)1924 (28.5)
  Three9918 (14.6)898 (13.3)
 Left main disease2637 (3.9)206 (3.0)0.00.001
 Stented59 207 (86.9)5986 (88.2)0.00.002
  Drug-eluting stent48 660 (82.2)5052 (84.4)<0.001
 Complete revascularisation4280 (69.7)4574 (73.5)8.8<0.001
  • CAD, coronary artery disease; CKD, chronic kidney disease according to the CKD-EPI formula; COPD, chronic obstructive pulmonary disease; DAPT, dual antiplatelet therapy; GFR, glomerular filtration rate; LMWH, low molecular weight heparin; STEMI, ST-segment elevation myocardial infarction; UA/NSTEMI, unstable angina/non-ST-segment elevation myocardial infarction.