Comparison of different parameters in computational flow dynamics (CFD) patients with and without CT-AVA≤1
| Parameter | Consistent grading (n=23) | Inconsistent grading (n=23) | P value |
| AVCS, median (IQR) | 3381 (2843–5000) | 2004 (1710–2793) | 0.001 |
| CFD-AVA, cm2, ±SD | 0.7±0.2 | 1.2±0.2 | <0.001 |
| CFD-Vmax±SD (m/s) | 7.2±2.3 | 5.7±1.3 | 0.01 |
| CFD peak PG, mm Hg, ±SD | 206±136 | 106±54 | 0.002 |
| CFD LVOT/AV velocity ratio (95% CI) | 0.11 (0.09 to 0.17) | 0.20 (0.16 to 0.23) | <0.001 |
| CFD-AV orifice velocity profile ratio, median (IQR) | 1.26 (1.16–1.45) | 1.24 (1.17–1.37) | 0.63 |
| CFD-AV orifice velocity profile ratio≥1.2 (%) | 14 (61) | 16 (70) | 0.53 |
| LVOT Qmax, cm3/s, mean±SD | 414±103 | 552±157 | 0.001 |
| LVOT Qmax≥450 (%) | 8 (35) | 19 (83) | 0.01 |
| Both CFD-AV orifice velocity ratio≥1.2 and LVOT Flow rate≥450 (%) | 5 (22) | 14 (61) | 0.007 |
AV, arotic valve; AVA, AV area; AVCS, AV calcium score; LVOT, left ventricular outflow tract; PG, pressure gradient; Qmax, maximum flow rate; Vmax, maximum flow velocity.