Predictive values of natriuretic peptides (NPs) on admission for future clinical adverse events
Variables | HR | 95% CI | P value |
(A) Univariate analysis | |||
Total ANP (per 10 pM) | 1.01 | 1.00 to 1.02 | 0.108 |
β-ANP (per 10 pM) | 1.14 | 0.93 to 1.37 | 0.185 |
Pro-ANP (per 10 pM) | 1.18 | 1.03 to 1.34 | 0.018 |
BNP (per 10 pM) | 1.02 | 0.99 to 1.03 | 0.101 |
Pro-BNP (per 10 pM) | 1.03 | 1.00 to 1.05 | 0.058 |
NT-pro-BNP (per 10 pM) | 1.00 | 1.00 to 1.01 | 0.002 |
(B) Age and sex-adjusted model | |||
Pro-ANP (per 10 pM) | 1.19 | 1.03 to 1.34 | 0.018 |
NT-pro-BNP (per 10 pM) | 1.00 | 1.00 to 1.01 | 0.002 |
(C) Age, sex and BMI-adjusted model | |||
Pro-ANP (per 10 pM) | 1.07 | 1.02 to 1.11 | 0.001 |
NT-pro-BNP (per 10 pM) | 1.00 | 1.00 to 1.01 | 0.001 |
(D) Age, sex and eGFR-adjusted model | |||
Pro-ANP (per 10 pM) | 1.05 | 1.00 to 1.10 | 0.046 |
NT-pro-BNP (per 10 pM) | 1.00 | 1.00 to 1.01 | 0.062 |
Values expressed per 10 pM increases of each NP.
ANP, A-type natriuretic peptide;BMI, body mass index; BNP, B-type natriuretic peptide; eGFR, estimated glomerular filtration rate.