Table 3

Estimates of the effect of location-specific scar % on the clinical and echocardiographic endpoints

Adjusted* estimate of HR
Septal scar†Anterior scar‡Lateral scar§Inferior scar¶
A: clinical endpointEstimateP valueEstimateP valueEstimateP valueEstimateP value
Time between CRT and death or heart failure admission1.030.0021.03<0.0011.030.0051.020.017
Adjusted* estimate of slope
Septal scar†Anterior scar‡Lateral scar§Inferior scar¶
B: echocardiographic endpointEstimateP valueEstimateP valueEstimateP valueEstimateP value
Change in EF after CRT−0.260.002−0.24<0.001−0.200.044−0.310.008
  • *Adjusted estimates are from a model where the following covariates were included as predictors (in addition to total scar %): age, gender, presence of left bundle branch block, QRS duration, diabetes mellitus and hypertension.

  • †Septal scar was calculated as the average of the scar per cent in AHA segments 2, 3, 8, 9 and 14.

  • ‡Anterior scar was calculated as the average of the scar per cent in AHA segments 1, 7 and 13.

  • §Lateral scar was calculated as the average of the scar per cent in AHA segments 5, 6, 11, 12 and 16.

  • ¶Inferior scar was calculated as the average of the scar per cent in AHA segments 4, 10 and 15.

  • AHA, American Heart Association; CRT, cardiac resynchronisation therapy; EF, ejection fraction.