Monozygotic twin pairs | Control pairs | Significance (Mann-Whitney U test, 2-tailed) | |||
DCM | LVEF | N | 8 | 11 | |
Age, years (median, IQR) | 51.4 (24.0) | 49.6 (25.6) | 0.52 | ||
Male (pairs, %) | 4 (50%) | 3 (27%) | 0.16 | ||
LVEF, % (median, IQR) | 32.0 (20.0) | 52.3 (31.7) | 0.001** | ||
LVEDD | N | 7 | 15 | ||
Age, years (median, IQR) | 45.9 (21.1) | 50.4 (29.4) | 0.30 | ||
Male (pairs, %) | 3 (43%) | 6 (40%) | 0.86 | ||
LVEDD, mm (median, IQR) | 55.5 (6.3) | 54.7 (7.8) | 0.41 | ||
HCM | IVSd | N | 11 | 14 | |
Age, years (median, IQR) | 30.3 (29.3) | 48.2 (33.3) | 0.06 | ||
Male (pairs, %) | 6 (55%) | 10 (71%) | 0.93 | ||
IVSd, mm (median, IQR) | 15.5 (8.3) | 11.5 (10.8) | 0.09 | ||
LQTS | QTc | N | 25 | 30 | |
Age, years (median, IQR) | 26.5 (46.8) | 32.3 (30.3) | 0.13 | ||
Male (pairs, %) | 13 (52%) | 14 (47%) | 0.58 | ||
QTc, ms (median, IQR) | 464 (49) | 462 (76) | 0.77 |
**Significant at the <0.01 level.
As not all data were complete for some pairs, the number of pairs in which we could assess certain traits differs from the number of pairs mentioned in table 1.
DCM, dilated cardiomyopathy; HCM, hypertrophic cardiomyopathy; IVSd, diastolic interventricular septum thickness; LQTS, long QT syndrome; LVEDD, left ventricular end-diastolic dimension; LVEF, left ventricular ejection fraction; QTc, corrected QT interval.