All patients (N=203) | With PHF (n=18) | Without PHF (n=185) | P value* | |
NT-proBNP POD1 (ng/L) | 2595 (1590–4065) | 6415 (3145–11220) | 2445 (1540–3855) | <0.0001 |
∆NT-proBNP POD1–PREOP (ng/L) | 1756 (1080–2750) | 3000 (1580–6295) | 1726 (1020–2590) | 0.023 |
NT-proBNP POD3 (ng/L) | 3920 (2590–6690) | 5530 (3370–8460) | 3840 (2540–6210) | 0.08 |
∆NT-proBNP POD3–PREOP (ng/L) | 3020 (1871–4760) | 2850 (925–4320) | 3040 (1891–4760) | 0.58 |
6-month follow-up NT-proBNP (ng/L) | 310 (170–730) | 340 (260–2310) | 300 (165–665) | 0.08 |
PPM | 79 (143/181) | 92 (11/12) | 78 (132/169) | 0.47 |
Severe PPM | 38 (69/181) | 42 (5/12) | 38 (64/169) | 0.77 |
ICU stay (hours) | 21 (17–23) | 21 (21–135) | 21 (17–22) | <0.0001 |
ICU stay >72 hours | 4 (8) | 33 (6) | 1 (2) | <0.0001 |
Ventilation time (hours) | 3 (2–5) | 8 (3–25) | 3 (2–5) | <0.0001 |
Ventilation time >48 hours | 2 (4) | 17 (3) | 0.5 (1) | 0.002 |
Postoperative stroke | 1 (2) | – | 1 (2) | 1 |
p-Troponin T POD3 (ng/L) | 290 (201–467) | 725 (414–838) | 272 (189–430) | <0.0001 |
p-CK-MB POD1 (μg/L) | 18 (13–25) | 30 (19–58) | 17 (13–24) | 0.002 |
p-CK-MB POD1 >50 µg/L | 4 (8) | 28 (5) | 2 (3) | <0.0001 |
PMI | 2 (4) | 17 (3) | 0.5 (1) | 0.002 |
p-Cystatin C POD3 (mg/L) | 1.34 (1.13–1.64) | 1.96 (1.41–2.36) | 1.32 (1.11–1.56) | <0.0001 |
Acute kidney injury | 10 (20) | 22 (4) | 9 (16) | 0.09 |
30-day mortality | 0.5 (1) | 0 | 0.5 (1) | 1 |
Data given as median (IQR) or percentage (n).
*PHF versus without PHF.
CK-MB, creatine kinase-MB isoenzyme;ICU, intensive care unit;NT-proBNP, N-terminal pro-B-type natriuretic peptide; p, plasma;PHF, postoperative heart failure;PMI, postoperative myocardial infarction;POD1, first postoperative day;POD3, third postoperative day;PPM, patient prosthesis mismatch; PREOP, the day before the index procedure.