Comparison of outcomes between the Ross operation, mechAVR and biological AVR: results from the meta-analysis
Cohorts | Ross | mechAVR | biological AVR | P value | |
Early mortality (%) | 46 | 0.24 (0.17 to 0.34) | 0.3 (0.19 to 0.45) | 0.28 (0.16 to 0.48) | 0.75 |
Total mortality (%/year) | 47 | 0.54 (0.45 to 0.64) | 1.38 (1.11 to 1.74) | 2.54 (1.8 to 3.59) | <0.001 |
AoV reoperation (%/year) | 47 | 0.54 (0.42 to 0.69) | 0.37 (0.27 to 0.5) | 1.28 (0.88 to 1.85) | <0.001 |
Bleeding (%/year) | 44 | 0.11 (0.06 to 0.20) | 0.69 (0.5 to 0.96) | 0.31 (0.14 to 0.69) | <0.001 |
Thromboembolic events (%/year) | 44 | 0.26 (0.19 to 0.37) | 0.86 (0.62 to 1.18) | 0.57 (0.39 to 0.84) | <0.001 |
AoV reoperations for IE (%/year) | 44 | 0.16 (0.12 to 0.2) | 0.17 (0.1 to 0.27) | 0.26 (0.18 to 0.39) | 0.08 |
Conservatively treated IE (%/year) | 46 | 0.21 (0.15 to 0.3) | 0.27 (0.18 to 0.42) | 0.29 (0.1 to 0.87) | 0.64 |
Total IE (%/year) | 39 | 0.34 (0.27 to 0.42) | 0.44 (0.3 to 0.64) | 0.63 (0.32 to 1.22) | 0.14 |
RVOT reinterventions (%/year) | 22 | 0.43 (0.34 to 0.54) |
Data are from random-effects models. Values in brackets are 95% CI.
AoV, aortic valve;IE, infective endocarditis;RVOT, right ventricular outflow tract; biological AVR, tissue aortic valve replacement;mechAVR, mechanical aortic valve replacement.