Mean concentration | Variance components | RCV† | II | ||||
CVG | CVI | CVA* | Normal | Log-normal | |||
BNP | 5.7 pmol/L | 48.4 (28.6 to 91.7) | 62.0 (52.5 to 75.4) | 19.7 (17.1 to 23.4) | ‡ | 52.6; −34.5 | 1.3 |
NT-proBNP | 9.3 pmol/L | 43.0 (27.7 to 88.8) | 22.0 (18.3 to 27.5) | 1.9 (1.6 to 2.3) | ‡ | 44.6; −30.9 | 0.5 |
hs-TnT | 9.2 ng/L | 57.2 (40.4 to 97.3) | 11.2 (9.6 to 13.5) | 3.7 (3.2 to 4.3) | ‡ | 43.1; −30.1 | 0.2 |
hs-TnI | 3.6 ng/L | 35.0 (23.3 to 67.6) | 9.2 (2.8 to 13.8) | 14.9 (12.7 to 18.0) | ‡ | 73.1; −42.2 | 0.5 |
ST2 | 28.4 ng/mL | 19.8 (13.8 to 33.4) | 13.1 (11.3 to 15.6) | 2.0 (1.7 to 2.4) | 36.83 | § | 0.7 |
Values are % (95% CI).
*On the basis of duplicate measurements.
†On the basis of a Z-score of 1.96.
‡Non-normal distribution.
§Normal distribution.
BNP, brain natriuretic peptide;CVA, analytical coefficient of variation; CVG, between-person coefficient of variation; CVI, within-person biological coefficient of variation; II, index of individuality; NT-proBNP, N-terminus pro-brain natriuretic peptide;RCV, reference change value; hs-TnI, high-sensitivity troponin-I; hs-TnT, high-sensitivity troponin-T.