Clinical characteristics and presenting symptoms according diagnoses (LLN-criteria)
| COPD + Ischemia - (n=42) | COPD - Ischemia + (n=51) | COPD + ischemia +(n=4) | Other spirometry finding + Ischemia - (n=22) | Normal findings (n=281) | P value | |
| Age, mean (SD) | 67.7 (10.3) | 66.4 (8.1) | 65.8 (4.6) | 65.3 (11.7) | 66.1 (10.9) | 0.902 |
| Sex, % women | 61.9 | 19.6 | 25.0 | 36.4 | 47.7 | <0.001 |
| Ever-smoker, % | 73.2 | 78.4 | 100.0 | 63.6 | 60.6 | 0.044 |
| Current-smoker, % | 24.4 | 13.7 | 50.0 | 9.1 | 9.3 | 0.008 |
| Known CAD, % | 31.0 | 54.9 | 100.0 | 59.1 | 27.9 | <0.001 |
| Chest discomfort, % | 61.9 | 76.5 | 50.0 | 63.6 | 74.0 | 0.294 |
| Dyspnea, % | 21.4 | 11.8 | 25.0 | 9.1 | 18.9 | 0.533 |
| FEV1 % of predicted | 74.8 (15.1) | 95.1 (15.3) | 59.5 (15.4) | 78.9 (13.9) | 96.0 (13.6) | <0.001 |
| VC % of predicted | 97.5 (17.0) | 91.9 (11.3) | 78.9 (13.8) | 73.7 (10.1) | 96.0 (12.2) | <0.001* |
| BMI, kg * m-2 | 29.2 (5.2) | 29.7 (4.5) | 26.1 (4.6) | 30.1 (5.1) | 28.0 (4.4) | 0.023 |
| Dyslipidaemia, % | 38.1 | 52.9 | 50.0 | 40.9 | 35.2 | 0.196 |
| SBP, mmHg | 138.1 (16.2) | 142.2 (17.3) | 131.3 (17.0) | 142.7 (15.3) | 138.1 (17.7) | 0.370 |
| DBP, mmHg | 79.9 (8.3) | 79.8 (8.2) | 85.0 (5.8) | 82.1 (12.3) | 79.7 (9.1) | 0.624 |
| Heart rate, bpm | 72.5 (11.7) | 71.0 (11.2) | 70.3 (14.1) | 70.9 (14.2) | 68.5 (11.5) | 0.230 |
P values are reported for ANOVA test for continuous variables and chi2 for dichotomous variables, unless otherwise specified.
*P value reported for Welch ANOVA test due to inhomogeneity of variances between groups.
BPM, beats per minute; CAD, coronary artery disease;DBP, diastolic blood pressure;DLCO, diffusion capacity for carbon monoxide;FEV1, forced expiratory volume in one second;LLN, lower limit of normal;SBP, systolic blood pressure;VC, vital capacity.