Table 1

Baseline characteristics of the study groups

RF-group (n=39)IMEA-group (n=17)CB-group (n=40)P value
Baseline data
 Age (years)64 (55–68)55 (50–64)59 (50–66)0.058
 BMI (kg/m2)26 (24–30)28 (25–34)26 (23–30)0.198
 Sex (male)28 (72)16 (94)35 (90)0.026
 Paroxysmal AF26 (67)2 (12)28 (70)<0.001
 Hypertension21 (54)11 (65)19 (48)0.489
 LVEF (%)59 (52–64)53 (46–61)60 (55–63)0.047
 LA diameter (mm)40 (37–45)44 (40–50)40 (36–44)0.045
Procedural data
 Net ablation duration (s)1834 (1584–2307)5382 (3614–6211)*1392 (1020–2010)<0.001
 Length of lesion (cm)24.0 (19.7–25.8)25.1 (21.3–31.7)22.2 (20.2–23.5)0.054
 hs-cTnT release (ng/L)828 (748–1044.0697 (519–945)834 (533–10270.618
 DeltaPerLength (ng/L/cm)36.0 (31.1–47.6)30.2 (17.0–43.1)37.1 (22.5–49.1)0.248
 DeltaPerDuration (pg/L/s)
 CK-MB release (U/L)
 CK release (U/L)
0.49 (0.34–0.54)
2 (1–3.5)
–2.5 (-41–24)
0.16 (0.11–0.20)
2 (1–3.5)
−8 (−34–22)
0.55 (0.39–0.72)
16 (11–21)
108 (36−169)
<0.001
<0.001
<0.001
  • Values are n (%) for categorical and mean±SD or median (25th–75th percentile) for continuous variables.

  • *Net ablation duration is reported cumulatively (from all electrodes) in the IMEA-group.

  • AF, atrial fibrillation; BMI, body mass index; CB, cryoballoon; CK, creatine kinase; CK-MB, creatine kinase MB isoenzyme; DeltaPerDuration, hs-cTnT release per duration of energy delivery; DeltaPerLength, hs-cTnT release per cm lesion; IMEA, irrigated multielectrode ablation; LA, left atrium; LVEF, left ventricular ejection fraction; RF, radiofrequency; duration, duration of energy delivery; hs-cTnT, high-sensitive cardiac troponin T.