Table 1

Demographic and clinical characteristics of included patients

CharacteristicStudy lead author
MenonFearonAliDilettiPouillotWijntjens
 Year201520172017201520172016
 DesignProspective, multicentreProspective, multicentreProspective, single centreNRProspective, single centreProspective, single centre
 Patients, no.5016974157728
 Lesions included, no.5216988158828
Patient baseline
 Age, mean, (SD), years66 (9)68 (9)64 (11)NR62 (11)62 (12)
 Male no. (%)40 (80)133 (79)54 (73)NR58 (75)22 (79)
 HTN no. (%)NR140 (83)71 (96)NR57 (74)15 (54)
 Smoking no. (%)NR23 (14)12 (16)NR24 (32)6 (21)
 Diabetes, no (%)NR63 (37)53 (72)NR34 (45)7 (25)
 Previous MI, no. (%)NR53 (31)NRNR23 (30)4 (14)
 BMI, mean (SD)NR31 (7)28.4 (NR)NR26.5 (4.3)NR
 Stable angina (%)NR123 (74)NRNR12 (16)NR
 Previous PCI, no. (%)NR75 (44)NRNR29 (38)8 (29)
Vessel characteristics
 Left main (%)620NRNRNR
 Left anterior descending (%)565249NRNRNR
 Left circumflex (%)131824NRNRNR
 Right (%)252626NRNRNR
 Mean diameter stenosis (%) (SD)56 (NR)*47 (9)66 (10)NR55 (9)52 (7)
 Mean RVD (mm) (SD)NR2.8 (0.5)2.5 (0.7)NR3.05 (0.55)2.64 (0.46)
 Mean FFRPW (SD)0.81 (0.11)0.83 (0.1)0.83 (0.09)0.85 (0.08)0.83 (0.07)0.86 (0.06)
 FFRPW 0.6–0.9 (%)717277807382
 Comparator pressure wireSt JudeSt Jude/Philips VolcanoSt JudeNRSt JudePhilips Volcano (Combowire)
 Adenosine administrationIntravenousIntravenousIntravenousNRIntravenousIntracoronary
  • *Reported as median value.

  • BMI, body mass index (weight in kilograms divided by height in metres squared); FFRPW, pressure wire fractional flow reserve; HTN, hypertension; MI, myocardial infarction; NR, not recorded; PCI, percutaneous coronary intervention; RVD, reference vessel diameter; mm, millimetres.