Outcome data according to resting heart rate subgroups, 1993
| All-cause death | Cardiovascular disease | Coronary heart disease | |||||||
| No events (%) ER (*1000 py) | HR (95% CI) P value | No events (%) ER (*1000 py) | HR (95% CI) P value | No events (%) ER (*1000 py) | HR (95% CI) P value | ||||
| Unadjusted | Adjusted | Unadjusted | Adjusted | Unadjusted | Adjusted | ||||
| RHR<55 (n=109) | 10 (9.2) | 1 (ref) | 1 (ref) | 23 (21.1) | 1 (ref) | 1 (ref) | 10 (9.2) | 1 (ref) | 1 (ref) |
| 4.3 | 10.0 | 0.003 | 4.3 | 0.753 | |||||
| 55≤RHR<65 (n=249) | 30 (12) | 1.3 (0.7 to 2.7) | 1.1 (0.5 to 2.3) | 67 (27.0) | 1.3 (0.8 to 2.1) | 1.3 (0.8 to 2.1) | 25 (10) | 1.1 (0.5 to 2.3) | 1.1 (0.5 to 2.3) |
| 5.7 | 0.432 | 0.807 | 12.8 | 0.234 | 0.274 | 4.8 | 0.757 | 0.826 | |
| 65≤RHR<75 (n=248) | 34 (13.7) | 1.5 (0.8 to 3.1) | 1.3 (0.6 to 2.6) | 75 (30.2) | 1.5 (1.0 to 2.4) | 1.4 (0.9 to 2.2) | 34 (13.7) | 1.5 (0.8 to 3.1) | 1.1 (0.5 to 2.4) |
| 6.5 | 0.245 | 0.530 | 14.4 | 0.234 | 0.189 | 6.5 | 0.231 | 0.742 | |
| RHR≥75 (n=192) | 45 (23.2) | 2.8 (1.4 to 5.5) | 2.3 (1.2 to 4.7) | 72 (37.5) | 2.1 (1.3 to 3.4) | 1.8 (1.1 to 3.0) | 44 (22.9) | 2.9 (1.4 to 5.7) | 2.2 (1.1 to 4.5) |
| 11.2 | 0.005 | 0.018 | 17.9 | 0.002 | 0.014 | 10.9 | 0.003 | 0.025 | |
Adjusted for body mass index, systolic blood pressure, smoking, sedentary lifestyle, mental stress, NT-pro-BNP and eGFR.
ER, event rate (1000 per year); NT-pro-BNP, N-terminal prohormone of brain natriuretic peptide; py, person years; RHR, resting heart rate; eGFR, estimated glomerular filtration rate.