Patient characteristics
| Variable | Cohort 1 228 patients | Cohort 2 23 patients |
| Age (years) | 60.3±9.7 | 61.0±11.0 |
| Male gender | 163 (71) | 16 (70) |
| Female gender | 65 (29) | 7 (30) |
| Hypertension | 117 (51) | 10 (43) |
| Hypercholesterolaemia | 131 (58) | 12 (52) |
| Smoking history | 88 (39) | 1 (4) |
| Diabetes mellitus | 49 (22) | 1 (4) |
| Previous myocardial infarction | 18 (8) | 0 (0) |
| Aspirin | 133 (58) | 14 (61) |
| Beta-blocker | 102 (45) | 3 (13) |
| Statin | 110 (48) | 14 (61) |
| Angiotensin-converting enzyme or angiotensin-II inhibitor | 33 (15) | 6 (26) |
| Calcium channel blocker | 38 (17) | 3 (13) |
Values are number (percentages) or mean±SD.