Matched OCT results | Baseline | Follow-up | Difference | P value |
Mean lumen area (mm2) | ||||
6 months | 6.8 (1.7) | 5.7 (1.4) | 1.1 (−1.3;−0.9) | <0.0001 |
9 months | 7.2 (1.6) | 5.6 (1.4) | 1.6 (−1.7;−1.4) | <0.0001 |
Minimal lumen area (mm2) | ||||
6 months | 5.3 (1.4) | 4.3 (1.3) | 1.0 (−1.3;−0.7) | <0.0001 |
9 months | 5.7 (1.4) | 4.1 (1.3) | 1.6 (−1.9;−1.4) | <0.0001 |
Mean scaffold area (mm2) | ||||
6 months | 7.1 (1.5) | 7.2 (1.4) | 0.1 (−0.02;0.24) | 0.12 |
9 months | 7.4 (1.5) | 7.3 (1.4) | −0.1 (−0.19;0.02) | 0.12 |
9 months | 7.4 (1.5) | 7.3 (1.4) | −0.1 (−0.19;0.02) | 0.13 |
Minimal scaffold area (mm2) | ||||
6 months | 5.9 (1.3) | 6.0 (1.3) | 0.1 (−0.02;0.25) | 0.08 |
9 months | 6.1 (1.4) | 6.1 (1.3) | −0.1 (−0.24;0.10) | 0.40 |
Mean extra scaffold lumen area (mm2)* | ||||
6 months | 0.05 (0.02;0.13) | 0.00 (0.00;0.02) | 0.04 (−0.11;−0.02) | <0.0001 |
9 months | 0.09 (0.04;0.19) | 0.00 (0.00;0.02) | 0.08 (-1.16;−0.03) | <0.0001 |
Mean neointimal area (mm2)* | ||||
6 months | 1.2 (1.0;1.4) | |||
9 months | 1.4 (1.1;1.7) | |||
Mean neointimal thickness (mm)* | ||||
6 months | 0.057 (0.040;0.077) | |||
9 months | 0.072 (0.056;0.101) | |||
Total analysed struts (N) | ||||
6 months | 20 696 | 20 233 | ||
9 months | 23 775 | 22 875 | ||
Mean strut count per analysis N (SD) | ||||
6 months | 283 (56) | 277 (57) | ||
9 months | 301 (62) | 290 (62) | ||
Malapposed struts (%)† | ||||
6 months | 0.8 (0.0;3.5) | 0.0 (0.0;0.0) | −0.7 (−3.5;0) | <0.0001 |
9 months | 1.8 (0.3;6.0) | 0.0 (0.0;0.0) | −1.5 (−5.1;−0.3) | <0.0001 |
Covered struts (%)† | ||||
6 months | 98.1 (95.9;99.4) | |||
9 months | 98.9 (98.3;100.0) | |||
Discontinued struts N (%)‡ | 2 (2.7) | 4 (5.5) | 2.7 (−2.4;7.9) | 0.16 |
6 months | 5 (6.3) | 16 (20.3) | 13.9 (2.9;24.9) | 0.01 |
9 months | 5 (6.3) | 16 (20.3) | 13.9 (2.9;24.9) | 0.01 |
Thrombus N (%)‡ | ||||
6 months | 48 (65.8) | 2 (2.7) | ||
9 months | 43 (54.4) | 2 (2.5) |
Matched data from the 73 patients in Cohort A and 79 patients in Cohort B. Results are mean (SD).
*Median (interquartile).
†Analysed on strut level, reported as median (IQR).
‡Analysed on patient level.
OCT, optical coherence tomography.