Table 1

Baseline patient characteristics, by microvascular function

VariableNormal microvascular endothelial function
(n=199)
Microvascular endothelial dysfunction
(n=258)
P value
Age, years51.9±12.354.4±11.60.03
Men, n (%)66 (33)78 (30)0.50
Vascular disease, n (%)16 (8)22 (9)5
Hypertension, n (%)76 (38)109 (43)0.34
Diabetes, n (%)15 (8)24 (9)0.50
Hyperlipidaemia, n (%)116 (59)148 (58)0.78
Depression, n (%)60 (31)61 (24)0.13
Smoking status, n (%)0.03
 Never smoked98 (49)150 (58)
 Former smoker77 (39)93 (36)
 Current smoker23 (12)15 (6)
Height, cm168.6±10.0167.6±9.20.29
Weight, kg79.8±19.180.6±20.30.68
Body mass index28.0±6.128.5±6.30.38
Haemoglobin, g/L135±13135±130.60
Glucose, mg/dL, median (Q1, Q3)95.0 (88.0, 105.0)96.0 (89.0, 104.0)0.49
Creatinine, mg/dL, median (Q1, Q3)1.0 (0.9, 1.1)1.0 (0.9, 1.1)0.58
Total cholesterol, mg/dL194.5±47.1191.4±43.40.49
LDL-C, mg/dL111.2±39.4110.1±38.10.77
HDL-C, mg/dL54.4±16.854.4±16.11.00
Triglycerides, mg/dL, median (Q1, Q3)121.0 (85.0, 176.5)113.5 (81.0, 171.0)0.32
hsCRP, mg/L, median (Q1, Q3)0.5 (0.2, 1.6)0.6 (0.2, 1.9)0.65
  • HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; hsCRP, high-sensitivity C reactive protein.