Multivariate Cox regression analyses for all-cause mortality in patients with moderate AS or AVR in patients with severe AS
| Moderate AS (n=204) | Severe AS (n=102) | |||
| All-cause mortality | AVR | |||
| HR (95% CI) | P value | HR (95% CI) | P value | |
| Rapid early rise in heart rate | 16.02 (1.83 to 140.02) | 0.012 | 3.21 (1.70 to 6.08) | <0.001 |
| Age, year | 1.13 (1.01 to 1.23) | 0.044 | 1.00 (0.97 to 1.03 | 0.897 |
| Male sex | 8.37 (0.43 to 165.06) | 0.162 | 2.16 (1.08 to 4.29) | 0.029 |
| Hypertension | 0.11 (0.01 to 2.11) | 0.143 | 0.90 (0.44 to 1.87) | 0.781 |
| Doppler stroke volume, mL | 1.00 (0.95 to 1.05) | 0.990 | 0.99 (0.98 to 1.01) | 0.733 |
| Mean pressure gradient, mm Hg | 1.17 (1.00 to 1.36) | 0.045 | 1.03 (1.00 to 1.05) | 0.043 |
| Abnormal blood pressure response | 0.19 (0.02 to 2.24) | 0.185 | 1.86 (1.00 to 3.44 | 0.049 |
| Coronary artery disease | 14.63 (0.42 to 514.15) | 0.140 | 1.35 (0.74 to 2.47) | 0.333 |
AS, aortic stenosis; AVR, aortic valve replacement.