Table 3

Invasive haemodynamic measurements at rest and during exercise according to regurgitated volume on cardiac MRI (CMRI)

	Rest			Peak exercise
	Regurgitant volume <60 mL	Regurgitant volume vol ≥60 mL	P value	Regurgitant volume <60 mL	Regurgitant volume ≥60 mL	P value
Watts at max. exercise	–	–	–	111±46	129±36	0.17
Estimated VO₂ (Fick), ml/kg	2.8±0.8	2.6±0.6	0.51	18.7±6.7	18.8±4.3	0.67
Heart rate	66±14	67±10	0.71	122±19	130±16	0.12
MAP, mm Hg	89±9	91±9	0.57	106±14	112±18	0.23
Mean RAP, mm Hg	6±3	7±4	0.52	11±6	10±4	0.97
PAP systolic, mm Hg	27±6	32±9	0.04	57±12	63±13	0.11
PAP diastolic, mm Hg	12±3	14±5	0.11	27±6	30±6	0.09
PAP mean, mm Hg	18±4	21±7	0.04	41±8	45±8	0.09
PCWP, mm Hg	11±3	14±4	0.002	27±7	28±7	0.44
CO, L/min	4.9±1.2	5.3±1.2	0.32	13.2±4.0	14.2±2.9	0.34
CI, l/min/m²	2.6±0.5	2.6±0.5	0.85	6.8±1.4	7.1±1.3	0.41
LV stroke work, g*m	138±31	186±34	<0.001
RV stroke work, g*m	7.4±3.9	7.2±5.8	0.89
PAPI	3.0±1.4	3.4±2.2	0.39	3.1±1.4	3.1±1.1	0.94
SVO₂	72±6	75±5	0.11	35±11	36±11	0.77
Lactate, mmol/L	0.6±0.3	0.6±0.2	0.79	4.1±1.7	5.3±1.8	0.04

Data are mean±SD.
CI, Cardiac Index; CO, cardiac output; LV, left ventricular; MAP, mean arterial pressure; PAP, pulmonary artery pressure; PAPI, Pulmonary Pulsatility Index; PCWP, pulmonary capillary wedge pressure; RAP, right atrial pressure; RV, right ventricular; SVO₂, mixed venous oxygen saturation; VO₂, maximal oxygen consumption.