ILD and contractility surrogates
All patients (n=27) | Acute CRT non-responder (n=9) | Acute CRT responder (n=18) | P value | |
ILD and FS | ||||
Baseline ILD end diastole (mm) | 102.8±23.0 | 103.3±30.4 | 102.6±22.7 | 0.32 |
Baseline ILD end systole (mm) | 91.4±20.7 | 89.9±30.3 | 91.7±21.7 | 0.43 |
Baseline FS (%) | 8.8±5.4 | 8.6±5.3 | 9.0±5.3 | 0.94 |
BIVP ILD end diastole (mm) | 100.9±18.1 | 100.2±26.1 | 101.3±22.3 | 0.38 |
BIVP ILD end systole (mm) | 91.9±22.6 | 91.1±31.0 | 92.7±22.3 | 0.40 |
BIVP FS (%) | 6.8±4.4 | 6.8±6.0 | 6.2±3.9 | 0.71 |
ΔFS (%) | −2.4±3.0 | −2.0±3.1 | −2.5±2.6 | 0.50 |
Time to peak systolic contraction | ||||
Baseline (ms) | 426±69 | 427±78 | 421±70 | 0.63 |
BIVP (ms) | 390±50 | 398±14 | 379±51 | 0.15 |
ΔTime to peak systolic contraction (%) | −10.8±12.6 | −10.8±15.1 | −9.7±18.1 | 0.43 |
Peak negative slope | ||||
Baseline (mm/s) | −45.0±17.7 | −48.0±17.8 | −41.2±21.9 | 0.23 |
BIVP (mm/s) | −53.9±34.8 | −46.7±28.4 | −61.5±45.9 | 0.18 |
Δpeak negative slope (%) | 2.7±45.0 | −8.7±45.9 | 12.5±54.8 | 0.09 |
ILD was calculated between the right ventricular lead tip electrode and the active left ventricular lead electrode. Variables are presented as median±IQR.
BIVP, biventricular pacing; CRT, cardiac resynchronisation therapy; FS, fraction shortening; ILD, interlead distance.