Table 3

ILD and contractility surrogates

All patients (n=27)Acute CRT non-responder (n=9)Acute CRT responder (n=18)P value
ILD and FS
 Baseline ILD end diastole (mm)102.8±23.0103.3±30.4102.6±22.70.32
 Baseline ILD end systole (mm)91.4±20.789.9±30.391.7±21.70.43
 Baseline FS (%)8.8±5.48.6±5.39.0±5.30.94
 BIVP ILD end diastole (mm)100.9±18.1100.2±26.1101.3±22.30.38
 BIVP ILD end systole (mm)91.9±22.691.1±31.092.7±22.30.40
 BIVP FS (%)6.8±4.46.8±6.06.2±3.90.71
 ΔFS (%)−2.4±3.0−2.0±3.1−2.5±2.60.50
Time to peak systolic contraction
 Baseline (ms)426±69427±78421±700.63
 BIVP (ms)390±50398±14379±510.15
 ΔTime to peak systolic contraction (%)−10.8±12.6−10.8±15.1−9.7±18.10.43
 Peak negative slope
 Baseline (mm/s)−45.0±17.7−48.0±17.8−41.2±21.90.23
 BIVP (mm/s)−53.9±34.8−46.7±28.4−61.5±45.90.18
 Δpeak negative slope (%)2.7±45.0−8.7±45.912.5±54.80.09
  • ILD was calculated between the right ventricular lead tip electrode and the active left ventricular lead electrode. Variables are presented as median±IQR.

  • BIVP, biventricular pacing; CRT, cardiac resynchronisation therapy; FS, fraction shortening; ILD, interlead distance.