Table 2

Structural outcomes after cardiovascular medication in a rat model of repetitive myocardial ischaemia

SHAM
n=7
ROP
n=6
NTG
n=6
MET
n=6
VER
n=7
RAN
n=7
CAN
n=6
Infarcted myocardium (%)*
Mean±SD16.2±6.26.6±3.35.9±3.59.9±4.414.2±4.114.6±10.115.5±4.4
95% CI10.4 to 21.93.3 to 10.02.3 to 9.65.2 to 14.510.4 to 18.05.3 to 24.010.8 to 20.1
P value (vs ROP)0.0080.7500.1750.0040.1040.003
P value (vs SHAM)0.0080.0060.0650.5020.7380.818
  • *Volume fraction of infarcted myocardium of the left ventricle after sustainedLAD occlusion and reperfusion.

  • CAN, candesartan group; LAD, left anterior coronary artery; MET, metoprolol group; NTG, nitroglycerin group; RAN, ranolazine group; ROP, repetitive occlusion protocol group; SHAM, control group without ROP; VER, verapamil group.