Baseline characteristics for the entire UK cohort, for patients free from diabetes and not receiving astatin, and according to QRISK2 (2017) 10-year cardiovascular risk
Overall (N=673) | Patients without DM who were not receiving statin treatment (N=305) | Low risk(<10%) (N=80) | Intermediate risk (10% to <20%) (N=110) | High risk (≥20%) (N=95) | |
Age, years | 65.0 (8.9) | 64.4 (9.4) | 55.6 (4.6) | 62.5 (5.6) | 72.7 (6.9) |
Men, n (%) | 344 (51.1) | 135 (44.3) | 19 (23.8) | 55 (50) | 54 (56.8) |
Dyslipidaemia, n (%) | 357 (53.0) | 68 (22.3) | 21 (26.3) | 23 (20.9) | 19 (20.0) |
Total cholesterol, mmol/L | 5.0 (1.2) | 5.7 (1.0) | 5.7 (0.9) | 5.7 (1.1) | 5.7 (1.0) |
LDL-C, mmol/L | 2.9 (1.0) | 3.5 (0.8) | 3.4 (0.7) | 3.5 (0.9) | 3.5 (0.9) |
HDL-C, mmol/L | 1.4 (0.4) | 1.5 (0.4) | 1.6 (0.5) | 1.5 (0.4) | 1.5 (0.4) |
Triglycerides, mmol/L | 1.7 (0.9) | 1.6 (0.9) | 1.4 (0.6) | 1.6 (0.8) | 1.7 (1.1) |
Hypertension, n (%) | 481 (71.5) | 223 (73.1) | 44 (55.0) | 84 (76.4) | 84 (88.4) |
SBP, mm Hg | 136.3 (15.9) | 137.2 (15.6) | 128.7 (13.5) | 137.8 (14.7) | 143.9 (14.6) |
DBP, mm Hg | 79.1 (9.9) | 80.1 (10.1) | 80.5 (9.3) | 82.3 (10.1) | 78.3 (9.8) |
DM, n (%) | 152 (22.6) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
BMI, kg/m2 | 29.3 (6.4) | 28.6 (6.2) | 28.9 (6.2) | 29.1 (5.1) | 28.5 (4.9) |
Obese, n (%) | 239 (35.5) | 97 (31.8) | 31 (38.8) | 35 (31.8) | 26 (27.4) |
Current smoker, n (%) | 110 (16.3) | 56 (18.4) | 40 (50.0) | 49 (44.5) | 52 (54.7) |
HsCRP, mg/L, median (IQR) | 2.1 (3.4) | 2.4 (3.6) | 2.1 (4.7) | 2.8 (4.1) | 2.3 (2.7) |
Data are mean (SD) unless otherwise indicated.
BMI, body mass index; DBP, diastolic blood pressure; DM, diabetes mellitus; HDL-C, high-density lipoprotein cholesterol; hsCRP, high-sensitivity C-reactive protein; LDL-C, low-density lipoprotein cholesterol; SBP, systolic blood pressure.