Preoperative drug therapy
| Drug class | IHHT group (n=40), abs. (%) | RIP group (n=40), abs. (%) | Control group (n=40), abs. (%) | P values |
| Antithrombotic drugs | ||||
| Aspirin | 40 (100%) | 37 (92.5%) | 38 (95%) | NS |
| Clopidogrel | 4 (10%) | 6 (15%) | 6 (15%) | NS |
| Statins | 32 (80%) | 34 (85%) | 29 (72.5%) | NS |
| Beta-blockers | 25 (62.5%) | 25 (62.5%) | 29 (72.5%) | NS |
| Calcium channel blockers | 18 (45%) | 17 (42.5%) | 20 (50%) | NS |
| ACE inhibitors | 26 (65%) | 30 (75%) | 23 (57.5%) | NS |
| ARB | 8 (20%) | 7 (17.5%) | 4 (10%) | NS |
| Prolonged nitrates | 7 (17.5%) | 4 (10%) | 8 (20%) | NS |
| Molsidomine | 2 (5%) | 1 (2.5%) | 0 | NS |
| Trimetazidine | 4 (10%) | 6 (15%) | 3 (7.5%) | NS |
| Amiodarone | 3 (7.5%) | 5 (12.5%) | 5 (12.5%) | NS |
ARB, angiotensin II receptor blocker; IHHT, intermittent hypoxic–hyperoxic training; NS, no significant difference between all three groups; RIP, remote ischaemic preconditioning.