Biomarker | Q1 | Q3 | Difference | Effect | 95% CI | P values |
hs-CRP (mg/L), IQR | 1.0 | 4.7 | 3.7 | 1.50 | 1.26 to 1.73 | <0.001 |
IL-6 (ng/L), IQR | 1.5 | 3.9 | 2.4 | 0.97 | 0.74 to 1.20 | <0.001 |
GDF-15 (mg/L), IQR | 974.0 | 2047.0 | 1073 | −0.60 | −8.84 to -0.36 | <0.001 |
Troponin T (ng/L), IQR | 7.5 | 16.6 | 9.1 | 0.31 | 0.07 to 0.55 | 0.004 |
NT-pro-BNP (ng/L), IQR | 362.0 | 1241.0 | 879.0 | −1.46 | −1.68 to -1.24 | <0.001 |
Cystatin C (mg/L), IQR | 0.8 | 1.2 | 0.4 | 1.18 | 0.93 to 1.43 | <0.001 |
Model adjusted for all variables in table 1.
GDF-15, growth differentiation factor-15; hs-CRP, high-sensitivity C reactive protein; IL-6, interleukin 6; NT-pro-BNP, N-terminal B-type natriuretic peptide.