Table 3

Baseline characteristics of men and women with HFpEF and HFrEF

VariableHFpEFHFrEF
Men
(n=1879)
Women
(n=873)
Men
(n=3726)
Women (n=1090)P values*
Age (mean±SD)68.57±9.5071.41±8.6567.54±10.0169.58±9.43<0.001
 40–64619 (32.9%)196 (22.5%)1406 (37.7%)324 (29.7%)<0.001
 65–74698 (37.1%)317 (36.3%)1291 (34.6%)389 (35.7%)
 75–84518 (27.6%)325 (37.2%)930 (25.0%)334 (30.6%)
 ≥8544 (2.3%)35 (4.0%)99 (2.7%)43 (3.9%)
Rurality282 (15.0%)121 (13.9%)532 (14.3%)153 (14.0%)0.64
Income quintile 1 (lowest)346 (18.4%)238 (27.3%)800 (21.5%)261 (23.9%)<0.001
 2422 (22.5%)192 (22.0%)810 (21.7%)244 (22.4%)
 3387 (20.6%)165 (18.9%)738 (19.8%)204 (18.7%)
 4380 (20.2%)152 (17.4%)669 (18.0%)208 (19.1%)
 5 (highest)334 (17.8%)125 (14.3%)687 (18.4%)161 (14.8%)
 Missing10 (0.5%)≤5 (0.1%)22 (0.6%)12 (1.1%)
Remote MI632 (33.6%)285 (32.6%)1618 (43.4%)454 (41.7%)<0.001
Recent MI920 (49.0%)498 (57.0%)2444 (65.6%)811 (74.4%)<0.001
Previous PCI387 (20.6%)155 (17.8%)599 (16.1%)177 (16.2%)<0.001
Hypertension1766 (94.0%)844 (96.7%)3395 (91.1%)1032 (94.7%)<0.001
Atrial fibrillation301 (16.0%)132 (15.1%)653 (17.5%)138 (12.7%)0.001
Cerebrovascular disease283 (15.1%)130 (14.9%)514 (13.8%)161 (14.8%)0.56
Peripheral vascular disease389 (20.7%)190 (21.8%)801 (21.5%)246 (22.6%)0.69
COPD/Asthma717 (38.2%)373 (42.7%)1345 (36.1%)445 (40.8%)<0.001
Diabetes1083 (57.6%)543 (62.2%)2261 (60.7%)761 (69.8%)<0.001
Morbid obesity710 (37.8%)244 (27.9%)1235 (33.1%)303 (27.8%)<0.001
Hypothyroidism29 (1.5%)41 (4.7%)47 (1.3%)31 (2.8%)<0.001
Anaemia185 (9.8%)133 (15.2%)355 (9.5%)137 (12.6%)<0.001
Dialysis128 (6.8%)49 (5.6%)205 (5.5%)63 (5.8%)0.26
Chronic renal disease242 (12.9%)106 (12.1%)478 (12.8%)129 (11.8%)0.79
Liver disease26 (1.4%)12 (1.4%)55 (1.5%)15 (1.4%)0.99
Primary tumour133 (7.1%)51 (5.8%)231 (6.2%)67 (6.1%)0.52
Metastatic tumour14 (0.7%)≤5 (0.2%)24 (0.6%)14 (1.3%)0.04
Dementia14 (0.7%)6 (0.7%)13 (1.2%)24 (0.6%)0.326
Frailty538 (28.6%)360 (41.2%)1022 (27.4%)447 (41.0%)<0.001
Emergent surgery107 (5.7%)62 (7.1%)431 (11.6%)159 (14.6%)<0.001
  • *P values were obtained using one-way analysis of variance test for means and χ2 test for categorical variables.

  • COPD, chronic obstructive pulmonary disease; HFpEF, heart failure with preserved ejection fraction;HFrEF, heart failure with reduced ejection fraction;MI, myocardial infarction;PCI, percutaneous coronary intervention.