Multivariable predictors of disability at 1 year post-CABG in the pooled analysis
| Variable | Main model | Cluster by site | Completeness of revascularisation added |
| HR (95% CI) | HR (95% CI) | HR (95% CI) | |
| HF group | |||
| pEF, no HF | Reference | Reference | Reference |
| rEF, no HF | 1.11 (0.99 to 1.25) | 1.11 (1.00 to 1.24) | 1.10 (0.98 to 1.24) |
| HFpEF | 1.81 (1.57 to 2.08) | 1.81 (1.61 to 2.04) | 1.79 (1.55 to 2.06) |
| HFrEF | 1.68 (1.49 to 1.90) | 1.68 (1.46 to 1.93) | 1.67 (1.48 to 1.89) |
| Age group | |||
| 40–64 | Reference | Reference | Reference |
| 65–74 | 1.14 (1.03 to 1.27) | 1.14 (1.02 to 1.27) | 1.13 (1.02 to 1.26) |
| 75–84 | 1.57 (1.40 to 1.77) | 1.57 (1.49 to 1.66) | 1.57 (1.40 to 1.76) |
| ≥85 | 1.91 (1.47 to 2.48) | 1.91 (1.41 to 2.57) | 1.87 (1.43 to 2.44) |
| Sex | 1.25 (1.13 to 1.37) | 1.25 (1.10 to 1.41) | 1.25 (1.13 to 1.38) |
| Rural residence | 0.97 (0.86 to 1.09) | 0.97 (0.90 to 1.04) | 0.97 (0.86 to 1.09) |
| Income quintile | |||
| 1 (lowest) | 1.27 (1.11 to 1.45) | 1.27 (1.12 to 1.43) | 1.29 (1.12 to 1.47) |
| 2 | 1.04 (0.91 to 1.20) | 1.04 (0.90 to 1.21) | 1.05 (0.91 to 1.21) |
| 3 | 0.99 (0.86 to 1.14) | 0.99 (0.88 to 1.12) | 1.01 (0.88 to 1.17) |
| 4 | 1.02 (0.89 to 1.18) | 1.02 (0.94 to 1.12) | 1.04 (0.90 to 1.20) |
| 5 (highest) | Reference | Reference | Reference |
| Missing | 1.81 (1.08 to 3.03) | 1.81 (0.85 to 3.86) | 1.83 (1.09 to 3.06) |
| Remote MI | 1.05 (0.95 to 1.15) | 1.05 (0.91 to 1.21) | 1.04 (0.95 to 1.15) |
| Recent MI | 1.32 (1.20 to 1.45) | 1.32 (1.15 to 1.51) | 1.31 (1.20 to 1.44) |
| Previous PCI | 0.96 (0.86 to 1.09) | 0.96 (0.85 to 1.09) | 0.98 (0.87 to 1.10) |
| Hypertension | 1.40 (1.16 to 1.68) | 1.40 (1.14 to 1.71) | 1.39 (1.15 to 1.68) |
| Atrial fibrillation | 1.21 (1.06 to 1.38) | 1.21 (1.08 to 1.35) | 1.21 (1.05 to 1.38) |
| Cerebrovascular disease | 2.16 (1.94 to 2.41) | 2.16 (1.96 to 2.39) | 2.18 (1.96 to 2.43) |
| Peripheral vascular disease | 1.34 (1.20 to 1.49) | 1.34 (1.22 to 1.46) | 1.34 (1.20 to 1.49) |
| COPD/Asthma | 1.33 (1.22 to 1.46) | 1.33 (1.22 to 1.45) | 1.34 (1.22 to 1.46) |
| Diabetes | 1.40 (1.28 to 1.53) | 1.40 (1.29 to 1.51) | 1.39 (1.27 to 1.52) |
| Morbid obesity | 1.02 (0.93 to 1.12) | 1.02 (0.96 to 1.08) | 1.03 (0.94 to 1.13) |
| Hypothyroidism | 1.16 (0.87 to 1.55) | 1.16 (0.83 to 1.62) | 1.16 (0.86 to 1.55) |
| Anaemia | 1.33 (1.14 to 1.55) | 1.33 (1.18 to 1.50) | 1.35 (1.16 to 1.57) |
| Chronic renal disease | 1.56 (1.36 to 1.79) | 1.56 (1.43 to 1.70) | 1.56 (1.36 to 1.79) |
| Liver disease | 1.79 (1.29 to 2.49) | 1.79 (1.41 to 2.27) | 1.81 (1.30 to 2.52) |
| Primary tumour | 1.23 (1.04 to 1.45) | 1.23 (1.05 to 1.44) | 1.21 (1.02 to 1.43) |
| Metastatic tumour | 1.28 (0.80 to 2.04) | 1.28 (0.84 to 1.95) | 1.32 (0.83 to 2.11) |
| Dementia | 1.85 (1.25 to 2.74) | 1.85 (1.36 to 2.51) | 1.83 (1.23 to 2.72) |
| Emergent surgery | 1.41 (1.22 to 1.63) | 1.41 (1.23 to 1.60) | 1.39 (1.20 to 1.61) |
| Incomplete revascularisation (yes) | – | – | 1.09 (1.00 to 1.20) |
CABG, coronary artery bypass grafting; COPD, chronic obstructive pulmonary disease; HF, heart failure; HFpEF, HF with preserved ejection fraction; HFrEF, HF with reduced ejection fraction; MI, myocardial infarction; PCI, percutaneous coronary intervention; pEF, preserved ejection fraction; rEF, reduced ejection fraction.