Table 3

Baseline characteristics of study patients and overnight change in exhaled H2 (ΔH2)

Decrease H2 Increase H2 P values
(ΔH2<0 ppm)(ΔH2≥0 ppm)
Male (%)45 (58)12 (40)0.101
General examination
  BMI (kg/m2)17.6±3.117.3±2.50.701
  Heart rate (bpm)69±1071±140.337
  Resting systolic BP (mm Hg)112±17112±150.910
  Resting diastolic BP (mm Hg)64±1363±100.570
Laboratory data
  Alb (g/dL)4.2±0.44.3±0.30.203
  UA (mg/dL)6.1±1.85.8±1.60.547
  eGFR (mL/min/1.73 m2)66.1 (53.1–72.6)64.6 (56.7–77.6)0.914
  Sodium (mEq/L)140.7±3.7140.8±2.70.900
  T-bil (mg/dL)0.8±0.40.9±0.60.181
  CRP (mg/dL)0.24±0.520.09±0.110.120
  hsTnT (ng/mL)0.014 (0.008–0.022)0.007 (0.004–0.018)0.284
  BNP (pg/mL)148 (74–301)186 (100–275)0.601
  LV ejection fraction (%)48±1549±180.765
  LA volume index (mL/m2)62 (39–88)64 (49–83)0.367
E/e′ ratio13.6±6.015.0±6.90.342
  TRPG (mm Hg)30.1±10.325.6±8.90.059
Haemodynamic data
  Mean PCWP (mm Hg)11.3±5.811.8±6.60.717
  Mean PAP (mm Hg)19.0±6.118.9±7.30.932
  Mean RAP (mm Hg)4.0±2.35.2±4.10.077
  CI (L/min/m2)2.85±0.63.24±0.70.005
  SvO2 (%)68.7±6.268.6±4.80.962
  • Values are means±SD, median (IQR), or n (%).

  • Alb, albumin; BMI, body mass index; BNP, B-type natriuretic peptide; BP, blood pressure; CI, cardiac index; CRP, C-reactive protein; E/e', ratio of early transmitral velocity to tissue Doppler mitral annular velocity during early diastole; eGFR, estimated glomerular filtration rate; hsTnT, high-sensitivity troponin T; LA, left atrial; LV, left ventricular; PAP, pulmonary artery pressure; PCWP, pulmonary capillary wedge pressure; RAP, right atrial pressure; SvO2, mixed venous oxygen saturation; T-bil, total bilirubin; TRPG, tricuspid regurgitation pressure gradient; UA, uric acid.