Table 1

The distributions of standard predictors in the placebo group and in the group of patients who received clarithromycin

Standard predictorsPlacebo patients(n=2199)Clarithromycin patients(n=2172)
Demographics and history
Sex (male), n (%)1518 (69.0)1514 (69.7)
Age/year, mean (SD)65.2 (10.4)65.4 (10.3)
Smoking status (smoking, ex-smoker, never smoked), n (%)Smokers, 753 (34.2)
Ex-smokers, 1011 (46.0)
Never smoked, 435 (34.2)
Smokers, 819 (37.6)
Ex-smokers, 982 (45.2)
Never smoked, 371 (17.1)
Hypertension, n (%)883 (40.2)878 (40.4)
Diabetes, n (%)337 (15.3)341 (15.7)
Previous AMI, n (%)1494 (67.9)1470 (67.7)
Current medication
Aspirin, n (%)1937 (88.1)1902 (87.6)
Beta-blocker, n (%)681 (31.0)653 (30.1)
Calcium antagonist, n (%)772 (35.1)755 (34.8)
ACE inhibitor, n (%)577 (26.3)604 (27.8)
Long-lasting nitrate, n (%)457 (20.8)453 (20.9)
Diuretics, n (%)773 (35.2)762 (35.1)
Digoxin, n (%)126 (5.7)154 (7.1)
Statins, n (%)904 (41.1)896 (41.3)
Antiarrhythmic drugs, n (%)51 (2.3)55 (2.5)
Biochemical predictors
Log (CRP/mg/L) mean (SD), n*1.03 (1.12) 21591.07 (1.15) 2128
ApoA1/mg/dL mean (SD), n1.70 (0.34) 20761.70 (0.36) 2041
Log (ApoB/mg/dL) mean (SD), n0.16 (0.27) 20750.15 (0.27) 2040
Chol-HDL/mmol/L mean (SD), n1.02 (0.32) 20741.02 (0.32) 2039
Chol-LDL/mmol/L mean (SD), n2.56 (0.72) 20792.55 (0.73) 2044
Log(cholesterol/mmol/L) mean (SD), n1.73 (0.20) 20751.72 (0.20) 2039
Log(triglyceride/mmol/L) mean (SD), n0.73 (0.53) 20780.71 (0.52) 2040
Glomerular filtration rate (GFR/mL/min) mean (SD), n71.8 (19.2) 207972.1 (19.2) 2044
  • *The value of n varies because the laboratory tests have missing values.

  • AMI, acute myocardial infarction; Chol, cholesterol; CRP, C-reactive protein; HDL, high-density lipoprotein; LDL, low-density lipoprotein; Log, natural logarithm.