Standard predictors | Placebo patients(n=2199) | Clarithromycin patients(n=2172) |
Demographics and history | ||
Sex (male), n (%) | 1518 (69.0) | 1514 (69.7) |
Age/year, mean (SD) | 65.2 (10.4) | 65.4 (10.3) |
Smoking status (smoking, ex-smoker, never smoked), n (%) | Smokers, 753 (34.2) Ex-smokers, 1011 (46.0) Never smoked, 435 (34.2) | Smokers, 819 (37.6) Ex-smokers, 982 (45.2) Never smoked, 371 (17.1) |
Hypertension, n (%) | 883 (40.2) | 878 (40.4) |
Diabetes, n (%) | 337 (15.3) | 341 (15.7) |
Previous AMI, n (%) | 1494 (67.9) | 1470 (67.7) |
Current medication | ||
Aspirin, n (%) | 1937 (88.1) | 1902 (87.6) |
Beta-blocker, n (%) | 681 (31.0) | 653 (30.1) |
Calcium antagonist, n (%) | 772 (35.1) | 755 (34.8) |
ACE inhibitor, n (%) | 577 (26.3) | 604 (27.8) |
Long-lasting nitrate, n (%) | 457 (20.8) | 453 (20.9) |
Diuretics, n (%) | 773 (35.2) | 762 (35.1) |
Digoxin, n (%) | 126 (5.7) | 154 (7.1) |
Statins, n (%) | 904 (41.1) | 896 (41.3) |
Antiarrhythmic drugs, n (%) | 51 (2.3) | 55 (2.5) |
Biochemical predictors | ||
Log (CRP/mg/L) mean (SD), n* | 1.03 (1.12) 2159 | 1.07 (1.15) 2128 |
ApoA1/mg/dL mean (SD), n | 1.70 (0.34) 2076 | 1.70 (0.36) 2041 |
Log (ApoB/mg/dL) mean (SD), n | 0.16 (0.27) 2075 | 0.15 (0.27) 2040 |
Chol-HDL/mmol/L mean (SD), n | 1.02 (0.32) 2074 | 1.02 (0.32) 2039 |
Chol-LDL/mmol/L mean (SD), n | 2.56 (0.72) 2079 | 2.55 (0.73) 2044 |
Log(cholesterol/mmol/L) mean (SD), n | 1.73 (0.20) 2075 | 1.72 (0.20) 2039 |
Log(triglyceride/mmol/L) mean (SD), n | 0.73 (0.53) 2078 | 0.71 (0.52) 2040 |
Glomerular filtration rate (GFR/mL/min) mean (SD), n | 71.8 (19.2) 2079 | 72.1 (19.2) 2044 |
*The value of n varies because the laboratory tests have missing values.
AMI, acute myocardial infarction; Chol, cholesterol; CRP, C-reactive protein; HDL, high-density lipoprotein; LDL, low-density lipoprotein; Log, natural logarithm.