Cox regression analysis showing unadjusted and adjusted HRs of clinical endpoints for 30-day, 1-year and 5-year time periods
Clinical event | Time from admission | Infarct vessel* | Unadjusted | Comorbidity adjustment | Expanded adjustment | |||
HR (95% CI) | P values | HR (95% CI) | P values | HR (95% CI) | P values | |||
Mortality | 30 days | LAD | 1.64 (1.44 to 1.88) | <0.001 | 1.89 (1.64 to 2.17) | <0.001 | 2.04 (1.78 to 2.35) | <0.001 |
LCx | 1.19 (0.98 to 1.46) | NS | 1.46 (1.20 to 1.79) | <0.001 | 1.47 (1.20 to 1.80) | <0.001 | ||
1 year | LAD | 1.52 (1.37 to 1.69) | <0.001 | 1.72 (1.54 to 1.91) | <0.001 | 1.85 (1.66 to 2.06) | <0.001 | |
LCx | 1.15 (0.98 to 1.34) | NS | 1.37 (1.18 to 1.61) | <0.001 | 1.38 (1.18 to 1.61) | <0.001 | ||
5 years | LAD | 1.25 (1.16 to 1.34) | <0.001 | 1.38 (1.28 to 1.48) | <0.001 | 1.46 (1.35 to 1.57) | <0.001 | |
LCx | 1.05 (0.94 to 1.16) | NS | 1.22 (1.10 to 1.36) | <0.001 | 1.22 (1.10 to 1.36) | <0.001 | ||
Reinfarction | 30 days | LAD | 1.13 (1.03 to 1.24) | <0.05 | 1.14 (1.04 to 1.26) | <0.01 | 1.22 (1.10 to 1.34) | <0.001 |
LCx | 1.14 (1.00 to 1.31) | <0.05 | 1.16 (1.01 to 1.33) | <0.05 | 1.16 (1.01 to 1.32) | <0.05 | ||
1 year | LAD | 1.06 (0.98 to 1.15) | NS | 1.08 (1.00 to 1.17) | NS | 1.19 (1.09 to 1.29) | <0.001 | |
LCx | 1.10 (0.99 to 1.23) | NS | 1.12 (1.00 to 1.25) | <0.05 | 1.12 (1.00 to 1.25) | <0.05 | ||
5 years | LAD | 1.00 (0.94 to 1.07) | NS | 1.02 (0.95 to 1.09) | NS | 1.12 (1.04 to 1.20) | <0.01 | |
LCx | 1.01 (0.92 to 1.11) | NS | 1.02 (0.93 to 1.13) | NS | 1.03 (0.93 to 1.13) | NS | ||
Stroke | 30 days | LAD | 2.33 (1.47 to 3.69) | <0.001 | 2.23 (1.40 to 3.54) | <0.01 | 2.45 (1.53 to 3.91) | <0.001 |
LCx | 2.38 (1.33 to 4.25) | <0.01 | 2.39 (1.34 to 4.29) | <0.01 | 2.46 (1.37 to 4.41) | <0.01 | ||
1 year | LAD | 1.25 (1.01 to 1.55) | <0.05 | 1.26 (1.02 to 1.56) | <0.05 | 1.38 (1.11 to 1.72) | <0.01 | |
LCx | 1.40 (1.05 to 1.85) | <0.05 | 1.47 (1.11 to 1.95) | <0.01 | 1.50 (1.13 to 1.99) | <0.01 | ||
5 years | LAD | 1.19 (1.04 to 1.36) | <0.05 | 1.19 (1.04 to 1.36) | <0.05 | 1.30 (1.13 to 1.49) | <0.001 | |
LCx | 1.16 (0.97 to 1.40) | NS | 1.21 (1.00 to 1.46) | <0.05 | 1.26 (1.04 to 1.51) | <0.05 | ||
Bleeding | 30 days | LAD | 1.04 (0.75 to 1.44) | NS | 1.03 (0.74 to 1.44) | NS | 1.03 (0.73 to 1.44) | NS |
LCx | 1.59 (1.06 to 2.37) | <0.05 | 1.63 (1.09 to 2.44) | <0.05 | 1.66 (1.11 to 2.49) | <0.05 | ||
1 year | LAD | 1.01 (0.87 to 1.18) | NS | 1.01 (0.87 to 1.18) | NS | 1.05 (0.90 to 1.23) | NS | |
LCx | 1.03 (0.82 to 1.28) | NS | 1.05 (0.84 to 1.30) | NS | 1.07 (0.86 to 1.33) | NS | ||
5 years | LAD | 0.95 (0.85 to 1.06) | NS | 0.95 (0.85 to 1.06) | NS | 1.01 (0.90 to 1.13) | NS | |
LCx | 0.97 (0.83 to 1.14) | NS | 0.99 (0.85 to 1.17) | NS | 1.02 (0.87 to 1.20) | NS | ||
Heart failure | 30 days | LAD | 3.12 (2.62 to 3.73) | <0.001 | 3.20 (2.68 to 3.82) | <0.001 | 3.42 (2.85 to 4.09) | <0.001 |
LCx | 1.62 (1.25 to 2.09) | <0.001 | 1.71 (1.32 to 2.21) | <0.001 | 1.72 (1.33 to 2.23) | <0.001 | ||
1 year | LAD | 2.39 (2.16 to 2.65) | <0.001 | 2.50 (2.26 to 2.78) | <0.001 | 2.74 (2.47 to 3.04) | <0.001 | |
LCx | 1.38 (1.19 to 1.61) | <0.001 | 1.46 (1.26 to 1.70) | <0.001 | 1.47 (1.27 to 1.72) | <0.001 | ||
5 years | LAD | 2.04 (1.88 to 2.20) | <0.001 | 2.12 (1.96 to 2.29) | <0.001 | 2.32 (2.14 to 2.52) | <0.001 | |
LCx | 1.26 (1.12 to 1.42) | <0.001 | 1.34 (1.19 to 1.51) | <0.001 | 1.36 (1.21 to 1.54) | <0.001 |
*HRs shown with RCA as the reference vessel (HR 1.00) and all p values are compared with RCA.
LAD, left anterior descending artery; LCx, left circumflex artery; RCA, right coronary artery.