Table 3

Examples based on proposed universal definition of cardiotoxicity

CardiotoxicityTimingDemographicSourceAffected substrate
DoxorubicinEarlyAdultAnthracyclineCardiomyopathy
LatePaediatricAnthracyclineCardiomyopathy
CarfilzomibAcuteAdultVEGFHypertension
PD1/PDL1LateAdultImmuneMyocarditis
  • PD1,┬áprogrammed cell death-1; PDL1,┬áprogrammed death-ligand 1 VEGF,┬ávascular endothelial growth factor.