Table 1

Characteristics of included studies

Author/studyYearCountryDesignSample sizeAge
(SD)		Male (%)Fontan procedure, n (%)Follow-upLate outcomeNOS
Diller et al 22 2010UK, Germany and
Italy		Retrospective cohort study32121±956APC/AVC: 150 (46.7).
EC/LT: 171 (53.3).		21 months

  1. All-cause mortality and transplantation.

  2. Cardiac-related hospitalisation.

8/9
Fernandes et al 23 2011USARetrospective cohort study14621.5 (range 16.0–51.6)54*4 years

  1. All-cause mortality.

  2. Combined endpoint (mortality or a new morbidity).

7/9
Ohuchi et al 24 2015JapanRetrospective cohort study33518±964APC: 19 (5.7).
LT: 94 (28).
EC: 222 (66.3).		3.1 years

  1. All-cause mortality.

  2. Unscheduled hospitalisation.

8/9
Nathan et al 26 2015USARetrospective cohort study253
(95)		19±958APC: 27%.
LT: 67%.
EC: 5%.
AVC: 1%.		5.5 years

  1. All-cause mortality and transplantation.

  2. Death, Fontan-related events or hospitalisation.

8/9
Egbe et al 25 2017USARetrospective cohort study145
(71)		24±363APC: 107 (74).
LT: 29 (20).
EC: 9 (6).		8 years

  1. Cardiovascular adverse events (death and cardiac surgery).

7/9
Atz et al 27 2017USARetrospective cohort study33421±4††9.4 years

  1. All-cause mortality and transplantation.

8/9
Cunningham et al 28 2017USARetrospective cohort study13026.6±9.558APC: 32 (25).
LT: 79 (61).
EC: 15 (12).
AVC: 4 (3).		1.4 years

  1. All-cause mortality and transplantation.

  2. Death, transplantation, Fontan-related events or hospitalisation.

8/9

  • *Not reported for the entire cohort.

  • †Reported in an earlier cross-section.

  • AVC, atrioventricular connection; APC, atriopulmonary connection; EC, extracardiac; LT, lateral tunnel; NOS, Newcastle-Ottowa Scale.