Patient characteristics | All patients (n=1993) | AKI (n=318) | No AKI (n=1675) | P values |
Age | 82.0±7.4 | 82.4±6.9 | 81.9±7.5 | 0.24 |
Female | 1013 (51.1%) | 157 (49.5%) | 856 (51.4%) | 0.55 |
Male | 971 (48.9%) | 160 (50.5%) | 811 (48.7%) | |
NYHA class 4 | 346 (18.9%) | 77 (25.8%) | 269 (17.6%) | 0.001 |
Atrial fibrillation | 641 (32.2%) | 126 (39.6%) | 515 (30.8%) | 0.002 |
COPD | 351 (17.6%) | 64 (21.1%) | 287 (17.2%) | 0.20 |
Diabetes | 712 (35.7%) | 142 (44.8%) | 570 (34.0%) | <0.001 |
Hypertension | 1714 (86.0%) | 275 (86.5%) | 1439 (85.9%) | 0.79 |
Lipids | 1442 (72.6%) | 237 (74.5%) | 1205 (72.2%) | 0.40 |
PVD | 301 (15.1%) | 51 (16.0%) | 250 (15.0%) | 0.63 |
Stroke or TIA | 323 (16.2%) | 55 (17.3%) | 268 (16.0%) | 0.57 |
Prior open heart surgery | 404 (24.4%) | 51 (19.8%) | 353 (25.2%) | 0.062 |
STS score | 5.8±5.0 | 7.0±6.3 | 5.6±5.4 | <0.001 |
EuroSCORE | 7.2±7.3 | 8.8±8.8 | 6.8±6.9 | <0.001 |
Pre-mean PG | 44.7±16.6 | 43.0±15.7 | 45.1±16.8 | 0.043 |
LVEF <40% | 217 (11.2%) | 47 (15.3%) | 170 (10.5%) | 0.015 |
BMI | 27.2±5.6 | 28.2±27.5 | 27.1±26.8 | 0.002 |
Weight (kg) | 73.0±16.2 | 75.8±17.1 | 72.5±15.9 | <0.001 |
CRCL | 50.6±22.7 | 44.6±21.4 | 51.7±22.8 | <0.001 |
Pre-TAVR creatinine (µmol/L) | 106.7±43.0 | 127.1±53.7 | 102.8±39.5 | <0.001 |
Haemoglobin | 119.4±16.1 | 114.2±15.5 | 120.3±16.1 | <0.001 |
Valve size | 26.5±2.4 | 26.5±2.5 | 26.4±2.4 | 0.59 |
Conscious sedation | 790 (47.3%) | 119 (44.8%) | 497 (47.8%) | 0.38 |
Non-femoral access site | 290 (14.6%) | 76 (23.9%) | 214 (12.8%) | <0.001 |
Valve in valve procedure | 106 (5.3%) | 8 (2.5%) | 98 (5.9%) | 0.015 |
Contrast dye (mL) | 125.3±63.5 | 131.0±73.7 | 124.2±61.3 | 0.173 |
AKI, acute kidney injury; BMI, body mass index; COPD, chronic obstructive pulmonary disease; CRCL, creatinine clearance; EuroSCORE, European System for Cardiac Operative Risk Evaluation; LVEF, left ventricle ejection fraction; NYHA, New York Heart Association functional classification; PG, peak gradient; PVD, peripheral vascular disease; STS score, Society of Thoracic Surgeons adult cardiac surgery risk score; TAVR, transcatheter aortic valve replacement; TIA, transient ischaemic attack.