Univariable associations of baseline characteristics and acute kidney injury
| Comorbidity | OR (95% CI) | P values |
| Age | 1.01 (0.99 to 1.03) | 0.24 |
| Male | 1.08 (0.85 to 1.37) | 0.55 |
| NYHA class 4 | 1.27 (1.1 to 1.47) | 0.001 |
| Atrial fibrillation | 1.48 (1.15 to 1.89) | 0.002 |
| COPD | 1.22 (0.89 to 1.64) | 0.20 |
| Diabetes | 1.57 (1.23 to 2.01) | <0.001 |
| Hypertension | 1.05 (0.75 to 1.50) | 0.79 |
| Lipids | 1.12 (0.86 to 1.48) | 0.40 |
| PVD | 1.09 (0.78 to 1.5) | 0.63 |
| Stroke or TIA | 1.1 (0.79 to 1.5) | 0.57 |
| Prior open heart surgery | 0.73 (0.53 to 1.02) | 0.063 |
| STS score | 1.04 (1.02 to 1.07) | <0.001 |
| EuroSCORE | 1.03 (1.02 to 1.05) | <0.001 |
| Pre-mean PG | 0.99 (0.98 to 1.00) | 0.048 |
| LVEF <40% | 1.54 (1.09 to 2.18) | 0.016 |
| BMI | 1.03 (1.01 to 1.05) | 0.002 |
| Weight (kg) | 1.01 (1.01 to 1.02) | 0.001 |
| CRCL | 0.98 (0.98 to 0.99) | <0.001 |
| Pre-TAVR creatinine | 1.01 (1.01 to 1.01) | <0.001 |
| Haemoglobin | 0.98 (0.97 to 0.98) | <0.001 |
| Valve size | 1.01 (0.97 to 1.07) | 0.58 |
| Conscious sedation | 0.83 (0.64 to 1.08) | 0.17 |
| Transapical access site | 2.00 (1.40 to 2.81) | <0.001 |
| Non-femoral access site | 2.14 (1.59 to 2.87) | <0.001 |
| Valve in valve | 0.42 (0.18 to 0.81) | 0.019 |
BMI, body mass index; COPD, chronic obstructive pulmonary disease; CRCL, creatinine clearance; EuroSCORE, European System for Cardiac Operative Risk Evaluation; LVEF, left ventricle ejection fraction; NYHA, New York Heart Association functional classification; PG, peak gradient; PVD, peripheral vascular disease; STS score, Society of Thoracic Surgeons adult cardiac surgery risk score; TAVR, transcatheter aortic valve replacement; TIA, transient ischaemic attack.