Difference of various parameters post-PTSMA between good and poor responders
| Good responders (n=29) | Poor responders (n=18) | P values | |
| Laboratory data | |||
| BNP before PTSMA (pg/mL) | 414.2 (161.6–788.6) | 326.8 (104.0–857.3) | 0.71 |
| BNP 3 months after PTSMA (pg/mL) | 144.2 (71.6–315.9) | 225.0 (92.6–624.8) | 0.26 |
| Ratio of BNP (after 3 months/before) | 0.43 (0.24–0.68) | 0.78 (0.62–0.93) | 0.002 |
| Echocardiographic variables before PTSMA | |||
| LVEDD (mm) | 43.0±3.9 | 43.8±5.8 | 0.58 |
| LVESD (mm) | 24.3±2.9 | 24.8±3.7 | 0.62 |
| IVST (mm) | 20.9±2.7 | 20.9±3.5 | 0.99 |
| LAD (mm) | 43.0±9.0 | 47.1±7.1 | 0.10 |
| E/e’ (lateral) | 17.2±9.9 | 16.9±7.9 | 0.93 |
| Moderate or severe MR, n (%) | 15 (51.7) | 12 (66.7) | 0.37 |
| Resting peak LVOT PG (mm Hg) | 94.4±38.9 | 102.6±34.4 | 0.47 |
| Echocardiographic variables at 12 months after PTSMA | |||
| LAD (mm) | 39.8±8.6 | 44.3±8.8 | 0.095 |
| E/e’ (lateral) | 12.7±6.1 | 15.8±7.2 | 0.14 |
| Moderate or severe MR, n (%) | 2 (6.9) | 3 (16.7) | 0.31 |
| Resting peak LVOT PG (mm Hg) | 27.4±26.6 | 48.0±36.7 | 0.08 |
| NYHA before PTSMA | 2.9±0.4 | 2.6±0.2 | 0.001 |
| NYHA at 12 months after PTSMA | 1.5±0.5 | 2.1±0.2 | <0.001 |
Data are expressed as mean±SD or median (quartiles), and number (%).
BNP, brain natriuretic peptide; IVST, intraventricular septal thickness; LAD, left atrial diameter; LVEDD, left ventricular end-diastolic diameter; LVESD, left ventricular end-systolic diameter; LVOT, left ventricular outflow tract; MR, mitral regurgitation; NYHA, New York Heart Association; PTSMA, percutaneous transluminal septal myocardial ablation; PG, pressure gradient.