Table 3

Difference of various parameters post-PTSMA between good and poor responders

Good responders
Poor responders
P values
Laboratory data
 BNP before PTSMA (pg/mL)414.2 (161.6–788.6)326.8 (104.0–857.3)0.71
 BNP 3 months after PTSMA (pg/mL)144.2 (71.6–315.9)225.0 (92.6–624.8)0.26
 Ratio of BNP (after 3 months/before)0.43 (0.24–0.68)0.78 (0.62–0.93)0.002
Echocardiographic variables before PTSMA
 LVEDD (mm)43.0±3.943.8±5.80.58
 LVESD (mm)24.3±2.924.8±3.70.62
 IVST (mm)20.9±2.720.9±3.50.99
 LAD (mm)43.0±9.047.1±7.10.10
 E/e’ (lateral)17.2±9.916.9±7.90.93
 Moderate or severe MR, n (%)15 (51.7)12 (66.7)0.37
 Resting peak LVOT PG (mm Hg)94.4±38.9102.6±34.40.47
Echocardiographic variables at 12 months after PTSMA
 LAD (mm)39.8±8.644.3±8.80.095
 E/e’ (lateral)12.7±6.115.8±7.20.14
 Moderate or severe MR, n (%)2 (6.9)3 (16.7)0.31
 Resting peak LVOT PG (mm Hg)27.4±26.648.0±36.70.08
 NYHA before PTSMA2.9±0.42.6±0.20.001
 NYHA at 12 months after PTSMA1.5±0.52.1±0.2<0.001
  • Data are expressed as mean±SD or median (quartiles), and number (%).

  • BNP, brain natriuretic peptide; IVST, intraventricular septal thickness; LAD, left atrial diameter; LVEDD, left ventricular end-diastolic diameter; LVESD, left ventricular end-systolic diameter; LVOT, left ventricular outflow tract; MR, mitral regurgitation; NYHA, New York Heart Association; PTSMA, percutaneous transluminal septal myocardial ablation; PG, pressure gradient.