Complications after initial heart valve intervention
| No. of patients with complications*, n (% of total patients) | ICU stay, n (% of patients with complication) | ICU stay in days, mean±SD | |||||||
| Year 1 | Year 2 | Year 3 | Year 4 | Year 1–4 | Year 1–4 | ||||
| SVR | TVI | SVR | SVR | SVR | SVR | TVI | SVR | TVI | |
| Children (0–18 years) (n) | 411 | 0 | 406 | 405 | 405 | ||||
| All-cause mortality | 5 (1.2) | 1 (0.2) | |||||||
| Complications (total) | 25 (6.1) | 12 (3.0) | 4 (1.0) | 2 (0.5) | 16 (39.0) | ||||
| Acute kidney injury | 2 (0.5) | 1 (50.0) | 2.0±. | ||||||
| Atrial fibrillation | 4 (1.0) | 3 (0.7) | 1 (0.2) | ||||||
| Stroke | 1 (0.2) | ||||||||
| TIA | |||||||||
| Endocarditis | 4 (1.0) | 2 (0.5) | |||||||
| Myocardial infarction | |||||||||
| Pacemaker implantation | 1 (0.2) | 1 (0.2) | 2 (0.5) | ||||||
| Reintervention | 14 (3.4) | 5 (1.2) | 2 (0.5) | 1 (0.2) | 15 (68.2) | 2.1±1.1 | |||
| Young adults (19–60 years) (n) | 3213 | 33 | 3090 | 3056 | 3034 | ||||
| All-cause mortality | 123 (3.8) | 2 (6.1) | 34 (1.1) | 22 (0.7) | 5 (0.2) | ||||
| Complications (total) | 680 (21.2) | 6 (18.2) | 189 (6.1) | 98 (3.2) | 37 (1.2) | 130 (15.5) | 3 (50.0) | ||
| Acuty kidney injury | 26 (0.8) | 6 (0.2) | 1 (0.0) | 1 (0.0) | 6 (18.2) | 13.5±18.6 | |||
| Atrial fibrillation | 268 (8.3) | 1 (3.0) | 63 (2.0) | 40 (1.3) | 17 (0.6) | 8 (2.4) | 2.0±2.4 | ||
| Stroke | 154 (4.8) | 40 (1.3) | 18 (0.6) | 4 (0.1) | 26 (12.8) | 10.4±21.4 | |||
| TIA | 51 (1.6) | 29 (0.9) | 14 (0.5) | 2 (0.1) | 1 (1.2) | 2.0±. | |||
| Endocarditis | 118 (3.7) | 2 (6.1) | 37 (1.2) | 15 (0.5) | 8 (0.3) | 29 (18.2) | 1 (50.0) | 5.0±4.0 | 2.0±- |
| Myocardial infarction | 25 (0.8) | 8 (0.3) | 4 (0.1) | 1 (0.0) | 5 (13.5) | 17.8±32.6 | |||
| Pacemaker implantation | 90 (2.8) | 2 (6.1) | 10 (0.3) | 9 (0.3) | 1 (0.0) | 11 (10.1) | 3.7±2.5 | ||
| Reintervention | 39 (1.2) | 2 (6.1) | 18 (0.6) | 6 (0.2) | 3 (0.1) | 41 (65.1) | 2 (100.0) | 9.1±26.6 | 8.5±4.9 |
| Middle aged (61–70 years) (n) | 4826 | 70 | 4545 | 4472 | 4413 | ||||
| All-cause mortality | 281 (5.8) | 5 (7.1) | 73 (1.6) | 59 (1.3) | 15 (0.3) | ||||
| Complications (total) | 1167 (24.2) | 2 (2.9) | 300 (6.6) | 176 (3.9) | 67 (1.5) | 153 (10.7) | 1 (50.0) | ||
| Acute kidney injury | 57 (1.2) | 17 (0.4) | 5 (0.1) | 2 (0.0) | 10 (12.7) | 8.3±7.0 | |||
| Atrial fibrillation | 534 (11.1) | 138 (3.0) | 87 (1.9) | 31 (0.7) | 10 (1.6) | 2.7±2.2 | |||
| Stroke | 259 (5.4) | 53 (1.2) | 27 (0.6) | 11 (0.2) | 43 (12.9) | 5.8±5.1 | |||
| TIA | 113 (2.3) | 41 (0.9) | 32 (0.7) | 10 (0.2) | 8 (4.3) | 3.9±2.0 | |||
| Endocarditis | 153 (3.2) | 33 (0.7) | 17 (0.4) | 4 (0.1) | 29 (15.7) | 7.0±9.4 | |||
| Myocardial infarction | 45 (0.9) | 16 (0.4) | 9 (0.2) | 2 (0.0) | 8 (11.4) | 7.6±7.4 | |||
| Pacemaker implantation | 158 (3.3) | 1 (1.4) | 27 (0.6) | 12 (0.3) | 7 (0.2) | 14 (7.0) | 11.4±22.3 | ||
| Reintervention | 49 (1.0) | 1 (1.4) | 10 (0.2) | 5 (0.1) | 5 (0.1) | 28 (41.2) | 1 (100.0) | 4.5±6.3 | 1.0±. |
| Elderly (>70 years) (n) | 9527 | 809 | 8580 | 8315 | 8146 | ||||
| All-cause mortality | 947 (9.9) | 87 (10.8) | 265 (3.1) | 169 (2.0) | 61 (0.7) | ||||
| Complications (total) | 2436 (25.6) | 157 (19.4) | 678 (7.9) | 426 (5.1) | 125 (1.5) | 339 (11.2) | 18 (11.5) | ||
| Acute kidney injury | 135 (1.4) | 8 (1.0) | 14 (0.2) | 9 (0.1) | 29 (18.4) | 15.0±15.5 | |||
| Atrial fibrillation | 994 (10.4) | 26 (3.2) | 340 (4.0) | 211 (2.5) | 67 (0.8) | 33 (2.6) | 1 (3.8) | 6.9±13.1 | 2.0±. |
| Stroke | 670 (7.0) | 33 (4.1) | 155 (1.8) | 87 (1.0) | 19 (0.2) | 114 (12.9) | 6.5±6.4 | ||
| TIA | 220 (2.3) | 11 (1.4) | 66 (0.8) | 52 (0.6) | 13 (0.2) | 11 (3.3) | 2.8±1.5 | ||
| Endocarditis | 184 (1.9) | 8 (1.0) | 57 (0.7) | 23 (0.3) | 9 (0.1) | 36 (14.3) | 8.9±9.9 | ||
| Myocardial infarction | 112 (1.2) | 5 (0.6) | 33 (0.4) | 22 (0.3) | 7 (0.1) | 18 (10.9) | 4.4±4.8 | ||
| Pacemaker implantation | 428 (4.5) | 57 (7.0) | 67 (0.8) | 47 (0.6) | 13 (0.2) | 42 (7.6) | 4.9±4.6 | ||
| Reintervention | 76 (0.8) | 35 (4.3) | 9 (0.1) | 11 (0.1) | 2 (0.0) | 54 (55.1) | 16 (45.7) | 7.8±17.8 | 3.2±5.9 |
*Early complications are included in intervention DRG and therefore not included here.
DRG, Diagnosis Related Group; ICU, intensive care unit; MI, myocardial infarction; SVR, surgical heart valve replacement; TIA, transient ischaemic attack; TVI, transcatheter heart valve implantation.