Univariate predictors of cardiac death and composite outcome in patients with IMR
| Cardiac death | Cardiac death and heart failure | |||
| HR (95% CI) | P value | HR (95% CI) | P value | |
| Age | 1.04 (1.01 to 1.07) | 0.02 | 1.06 (1.04 to 1.09) | <0.001 |
| Male | 1.00 (0.44 to 2.29) | 0.99 | 1.47 (0.88 to 2.44) | 0.14 |
| Hypertension | 1.06 (0.55 to 2.02) | 0.87 | 1.62 (1.02 to 2.57) | 0.04 |
| Dyslipidaemia | 0.97 (0.50 to 1.86) | 0.92 | 1.01 (0.64 to 1.57) | 0.98 |
| Diabetes mellitus | 1.52 (0.79 to 2.94) | 0.21 | 1.69 (1.09 to 2.65) | 0.02 |
| Smoking | 1.22 (0.63 to 2.35) | 0.56 | 0.96 (0.61 to 1.53) | 0.87 |
| Killip classification | 2.54 (1.95 to 3.30) | <0.001 | 2.16 (1.77 to 2.64) | <0.001 |
| Peak CK | 1.15 (1.08 to 1.23) | <0.001 | 1.11 (1.05 to 1.17) | <0.001 |
| Creatinine | 1.30 (1.19 to 1.42) | <0.001 | 1.23 (1.14 to 1.34) | <0.001 |
| Prior MI | 2.37 (1.04 to 5.42) | 0.04 | 1.92 (1.04 to 3.54) | 0.04 |
| Anterior MI | 0.80 (0.42 to 1.54) | 0.51 | 1.23 (0.79 to 1.91) | 0.36 |
| PCI | 1.05 (0.37 to 2.96) | 0.93 | 0.70 (0.38 to 1.29) | 0.25 |
| Moderate or severe MR | 14.90 (7.74 to 28.68) | <0.001 | 5.13 (3.19 to 8.25) | <0.001 |
| β-blocker | 0.38 (0.20 to 0.73) | 0.004 | 0.41 (0.26 to 0.64) | <0.001 |
| Statins | 0.74 (0.39 to 1.43) | 0.37 | 0.62 (0.39 to 0.96) | 0.03 |
Per 1000 IU/L increments.
CK, creatine kinase; IMR, ischaemic mitral regurgitation; MI, myocardial infarction; PCI, percutaneous coronary intervention.