Cox hazard proportional regression multivariate analysis of risk factors: significant risk factors remaining in model after testing factors in table 4 (n=140; SD/CA n=27)
Parameter | B | SE | Exp (B) | Significance |
Only risk factors at diagnosis and early therapy entered (8.3% missing data in final model) | ||||
First limb-lead QRS sum | 0.073 | 0.031 | 1.076 | p=0.020 |
First SEPPER (septum in % of 95th centile) | 0.015 | 0.003 | 1.015 | p<0.001 |
LVOTO at rest (>20 mm Hg) | 0.206 | 0.107 | 1.229 | p=0.054 |
Early beta-blocker dose | −0.312 | 0.142 | 0.732 | p=0.028 |
(First ECG risk score | 0.208 | 0.090 | 1.231 | p=0.021) |
Predictors of sudden death at late follow-up (10.3% missing data in final model) | ||||
Last ECG risk score | 0.279 | 0.089 | 1.321 | p=0.002 |
Last Detroit Z-score (maximum wall thickness) | 0.550 | 0.161 | 1.733 | p=0.001 |
Beta-blocker+disopyramide therapy | −1.601 | 0.629 | 0.202 | p=0.011 |
(Last beta-blocker dose | −0.096 | 0.046 | 0.908 | p=0.037) |
LVOTO, left ventricular outflow tract obstruction; SD/CA, sudden death/cardiac arrest; SEPPER, septum in % of 95th centile for age. Within brackets: alternative values if first ECG risk score, or last beta-blocker dose, substituted into the respective models.