Table 2

Predictors of persistent acute kidney injury

	Univariate OR (95% CI)	p Value	Multivariable OR* (95% CI)	p Value
Age/10-year increase	0.77 (0.59 to 1.00)	0.052	0.85 (0.63 to 1.16)	0.312
eGFR/10 mL/min/1.73 m² increase	0.99 (0.98 to 1.00)	0.179	0.88 (0.79 to 0.98)	0.019
Contrast volume per 10 mL increase	1.03 (1.00 to 1.05)	0.028	1.02 (1.00 to 1.05)	0.052
Male	2.55 (1.61 to 4.04)	<0.001	2.68 (1.63 to 4.38)	<0.001
Known diabetes	1.30 (0.81 to 2.09)	0.280	1.09 (0.66 to 1.80)	0.735
LVEF
>50%	1.0 (ref)		1.0 (ref)
40%–49%	1.25 (0.72 to 2.19)	0.418	1.02 (0.57 to 1.81)	0.955
30%–39%	1.59 (0.91 to 2.78)	0.104	1.18 (0.66 to 2.12)	0.580
<30%	1.01 (0.45 to 2.28)	0.964	0.74 (0.32 to 1.72)	0.489
Logistic EuroSCORE I (n=1332)	1.88 (0.42 to 8.51)	0.407	–	–
Prosthesis make	Ref (CoreValve)		–	–
Edwards	0.96 (0.63 to 1.47)	0.856	–	–
Other	0.21 (0.03 to 1.53)	0.119		–
COPD	1.84 (1.17 to 2.91)	0.009	1.59 (0.99 to 2.59)	0.057
Bleeding complication	1.40 (0.51 to 2.78)	0.978	1.64 (0.81 to 3.33)	0.169
Access site	1.0 (ref: transfemoral)		1.0 (ref: transfemoral)
Apical	2.30 (1.47 to 3.79)	<0.001	2.23 (1.35 to 3.69)	0.002
Subclavian	1.31 (0.31 to 5.63)	0.713	1.34 (0.30 to 5.94)	0.697
Direct aortic	3.17 (0.91 to 11.1)	0.070	3.54 (0.95 to 13.3)	0.060
Prior CABG/PCI	1.26 (0.83 to 1.92)	0.278	0.90 (0.57 to 1.42)	0.658

The following interaction terms were tested: gender and contrast volume to creatinine clearance ratio: p value 0.321; gender and age: p value 0.770; gender and diabetes: p value 0.995; gender and access site: p value 0.465.
*The multivariable model was adjusted for age, sex, LVEF, baseline eGFR, contrast volume, COPD, diabetes, known hypertension, prior coronary revascularisation, bleeding complication and procedural access site.
CABG, coronary artery bypass graft; COPD, chronic obstructive pulmonary disease; eGFR, estimated glomerular filtration rate; LVEF, left ventricular ejection fraction; PCI, percutaneous coronary intervention.