BMS (n=18) | MSG (n=19) | p Value | ||
Quantitative findings | Minimum lumen area (mm2) | 4.4 (3.3–6.6) | 4.6 (3.7–5.7) | 0.68 |
NIH at minimum lumen area site (%) | 21.5 (9.7–30.4) | 20.3 (11.2–26.2) | 0.72 | |
Minimum stent area (mm2) | 5.85 (4.3–6.9) | 5.5 (4.4–6.3) | 0.47 | |
Proximal reference lumen area (mm2) | 6.5 (5.9–8.8) | 6.9 (5.0–8.3) | 0.72 | |
Distal reference lumen area (mm2) | 6.2 (3.4–7.5) | 5.3 (4.3–7.5) | 0.69 | |
Stent length by OCT (mm) | 18.4 (18.2–19.6) | 18.2 (17.8–22.6) | 0.52 | |
Lumen area (mm3/mm) | 6.2 (3.9–7.8) | 5.7 (5.0–6.9) | 0.71 | |
Stent area (mm3/mm) | 6.8 (5.4–8.0) | 6.3 (5.8–7.1) | 0.54 | |
Neointimal thickness (stent level) (mm) | 0.095 (0.06–0.17) | 0.085 (0.07–0.12) | 0.81 | |
Neointimal thickness (strut level) (mm) | 0.09 (0.04–0.17) | 0.07 (0.04–0.15) | 0.83 | |
NIH area (mm3/mm) | 0.7 (0.3–1.3) | 0.6 (0.4–0.9) | 0.83 | |
%NIH volume (=NIH/stent volume) (%) | 11.0 (3.9–21.5) | 8.9 (5,7–13.6) | 0.86 | |
Strut level findings | Total struts analysed | 198 (184–226) | 209 (195– 257) | 0.17 |
A. Definitely uncovered (%) | 0 (0–0) | 0 (0–0) | 0.97 | |
B. Covered with fibrin (%) | 0 (0–0) | 0 (0–0) | 0.71 | |
C. Partially covered (%) | 1.7 (0.4–4.6) | 2.83 (0.3–7.5) | 0.74 | |
D. Covered-protruding (%) | 17.4 (3.5–41.7) | 18.68 (12.3–34.9) | 0.95 | |
E. Covered-embedded (%) | 81.2 (49.8–95.5) | 74.21 (58.9–86.4) | 0.90 | |
Fully uncovered (A+B) (%) | 0.0 (0.0–0.5) | 0.0 (0–0.5) | 0.94 | |
Malapposed (%) | 0 (0–1.02) | 0 (0–2.6) | 0.80 | |
Qualitative findings | Homogeneous NIH (%) | 76.5% | 72.2% | 1.00 |
Heterogeneous NIH (%) | 17.6% | 27.8% | 0.69 | |
Layered NIH (%) | 5.9% | 0.0% | 0.49 | |
NIH with macrophage (%) | 0 (0.0%) | 1 (5.3%) | 1.00 | |
NIH with peri-strut microvessel (%) | 2 (11.1%) | 1 (5.3%) | 0.60 | |
NIH with any thrombus (%) | 2 (11.8%) | 2 (10.5%) | 1.00 | |
Any malapposition (%) | 7 (38.9%) | 8 (42.1%) | 0.84 | |
Length of malapposition (mm) | 2.4 (0.4–4.2) | 1.9 (1.4– 5.5) | 0.91 |
Median and IQR.
BMS, bare metal stent; MSG, microengineered stent grooves; NIH, neointimal hyperplasia.