Table 2

LV volumes, EF and diastolic parameters evaluated by echocardiography in 80 healthy individuals, 100 HCM LVH− patients and 180 HCM LVH+ patients

Healthy individuals (n=80) HCM LVH− patients (n=100) HCM LVH+ patients (n=180) p Value
EDV/BSA (mL/m2)57±1449±13* 41±14*† <0.001
ESV/BSA (mL/m2)23±919±6* 16±7*† <0.001
EF (%)61±660±561±70.43
GLS (%)−22.3±3.7−21.3±2.4−16.4±3.7*† <0.001
E (m/s)0.7±0.20.8±0.20.8±0.80.24
E/A ratio1.4±0.51.6±0.61.3±0.7 0.04
Deceleration time (ms)195±48175±30217±74*† <0.001
E/e′6.4±2.17.0±2.214.9±8.3*† <0.001
e′ (m/s)0.12±0.030.06±0.03* 0.11±0.04*† <0.001
LA area (cm2)17.0±4.116.3±4.524.9±11.3*† <0.001
  • The values are represented as mean±SD.

  • p values are based on Student’s t-test.

  • *p<0.05 compared with healthy individuals.

  • †p<0.05 compared with HCM LVH− patients.

  • A, atrial transmitral filling velocity; BSA, body surface area; e′, early diastolic myocardial velocity; E, early transmitral flow velocity; EDV, end-diastolic volume; EF, ejection fraction; ESV, end-systolic volume; GLS, global longitudinal strain; HCM, hypertrophic cardiomyopathy; HCM LVH−, HCM patients without increased wall thickness; HCM LVH+, HCM patients with increased wall thickness; LA, left atrium; LV, left ventricle; LVH, left ventricular hypertrophy.