Table 1

Baseline data

Overall cohortAborted SCA eventNo event
n521636
Age, years50.1±15.851.9±14.149.3±16.7
 Male33 (63.5%)10 (62.5%)23 (63.8%)
Sudden death risk factors
 Mean (range)1.29 (1-3)1.5 (1-3)1.2 (1-3)
 137 (71.1%)8 (50.0%)28 (77.8%)
 2+15 (28.8%)8 (50.0%)8 (22.2%)
 Family history of SCD21 (41.1%)8 (50.0%)13 (36.1%)
 Unexplained syncope13 (25.0%)4 (25.0%)9 (25.0%)
 LV wall thickness >30 mm9 (17.3%)3 (18.8%)6 (16.6%)
 Non-sustained VT on ambulatory holter24 (52.1%)9 (56.2%)15 (41.6%)
 Percentage of risk of SCD at 5 years—HCM risk-SCD*6.5±3.67.4±4.36.3±3.7
NYHA functional class
 I18 (34.6%)5 (31.3%)13 (36.1%)
 II20 (38.4%)7 (43.8%)13 (36.1%)
 III-IV14 (26.9%)4 (25.0%)10 (27.8%)
 Surgical myomectomy9 (17.3%)3 3 (18.8%)6 6 (16.6%)
 Alcohol ablation3 (5%)0 (0%)3 (8.3%)
  • Values are n (%), or mean±SD.

  • *Data on % risk of SCD at 5 years—HCM risk-SCD were available for 44 patients.

  • HCM, hypertrophic cardiomyopathy; NYHA, New York Heat Association; SCA, sudeen cardiac arrest; SCD, sudden cardiac death; VT, ventricular tachycardia.