The sensitivities, specificities, and PPV and NPV for (ECG) septal remodelling in classifying LMNA mutation carriers from the DCM controls, healthy controls or the combined control group of DCM controls and healthy controls
| Septal remodelling, N (%) | Current or previous AV block, flat P wave or septal remodelling, N (%) | |
|---|---|---|
| LMNA mutation carriers | 22 (81.5) | 26 (96.3) |
| Healthy controls | 0 | 0 |
| DCM controls | 16 (20.5) | 32 (41.0) |
| LMNA vs DCM controls | Per cent | Per cent |
| Sensitivity | 81.5 | 96.3 |
| Specificity | 79.5 | 59.0 |
| PPV | 57.9 | 44.8 |
| NPV | 92.5 | 97.9 |
| LMNA vs healthy controls | ||
| Sensitivity | 81.5 | 96.3 |
| Specificity | 100 | 100 |
| PPV | 100 | 100 |
| NPV | 80 | 95.2 |
| LMNA vs DCM or healthy controls | ||
| Sensitivity | 81.5 | 96.3 |
| Specificity | 83.7 | 67.3 |
| PPV | 57.9 | 44.8 |
| NPV | 94.3 | 98.5 |
DCM, dilated cardiomyopathy; NPV, negative predictive value; PPV, positive predictive value.