Pooled results
| Outcome | Pooled estimate (95% CI) | Number of studies reporting outcome (participants) |
|---|---|---|
| Complications before discharge | ||
| Reoperation during index admission, proportion | 0.054 (0.010 to 0.099)* | 5 (422),16–19 25 |
| Neurologic event, proportion | 0.007 (0.000 to 0.018)* | 4 (976)16 18 24 25 |
| Mortality | ||
| 30-day survival, proportion | 0.995 (0.991 to 0.999) | 9 (1844)15–20 23–25 |
| Survival at 1 year, proportion | 0.994 (0.989 to 0.999) | 5 (1038)16 17 20 24 25 |
| Survival at 5 years, proportion | 0.945 (0.898 to 0.993)* | 4 (1009)17 23–25 |
| Survival at 10 years, proportion | 0.912 (0.845 to 0.979)* | 2 (836)17 24 |
| Valve-related late mortality at follow-up | ||
| Proportion | 0.008 (0.000 to 0.019) | 7 (584)16–20 23 25 |
| Per 100 patient-years | 0.2 (0.0 to 0.4) | 7 (584)16–20 23 25 |
| Complications at follow-up | ||
| Operated valve endocarditis | ||
| Proportion | 0.011 (0.002 to 0.020) | 8 (615)16 18–23 25 |
| Per 100 patient-years | 0.3 (0.0 to 0.6) | 8 (615)16 18–23 25 |
| Thrombosis, embolism, and bleeding | ||
| Proportion | 0† | 4 (304)16 20 23 25 |
| Per 100 patient-years | 0† | 4 (304)16 20 23 25 |
| Reinterventions at follow-up | ||
| Reinterventions on operated valve at follow-up | ||
| Proportion | 0.075 (0.037 to 0.113)* | 10 (1944)15–18 20–25 |
| Per 100 patient-years | 1.3 (0.7 to 1.9)* | 9 (1385)16–18 20–25 |
| Freedom from reintervention at 1 year | 0.952 (0.938 to 0.967) | 2 (799)16 24 |
| Freedom from reintervention at 5 years | 0.934 (0.874 to 0.993)* | 5 (1026)16 22–25 |
| Freedom from reintervention at 10 years | 0.800 (0.760 to 0.839)* | 2 (1287)15 24 |
The table shows the number of studies reporting each outcome and the corresponding number of participants in these studies.
*Weights from random effects analysis. Results without indicator are from fixed-effect analysis with inverse variance weighting.
†No CIs computed because of 0 variance in all four studies reporting the outcome.